1271-55-2

Basic information

• Product Name: Acetylferrocene
• Synonyms: Ferrocenyl methyl ketone, 99+%;Iron, (acetylcyclopentadienyl)cyclopentadienyl-;Acetylferrocene,95%;Acetylferrocene ,98%;NSC 115511;ACETYLFERROCENE FOR SYNTHESIS;1-Ferrocenylethanone;ACETYLFERROCENE
• CAS NO: 1271-55-2
• Molecular Formula: C₁₂H₁₂FeO
• Molecular Weight: 228.07
• EINECS: 215-043-2
• Product Categories: Ferrocene series;metallocene;1,2,4-Triazole,Triazoles;Industrial/Fine Chemicals
• Mol File: 1271-55-2.mol
• Article Data: 183

Chemical Properties

• Melting Point: 81-83 °C(lit.)
• Boiling Point: 160-163 °C (3.0004 mmHg)
• Flash Point: 160-163°C/4mm
• Appearance: Orange/Needle-Like Crystalline Powder
• Density: >1 g/cm3 (20℃)
• Vapor Pressure: 1.77mmHg at 25°C
• Refractive Index: 1.502
• Storage Temp.: Store below +30°C.
• Water Solubility: insoluble
• Stability: Stable. Incompatible with strong oxidizing agents, reducing agents, strong acids, strong bases.
• CAS DataBase Reference: Acetylferrocene(CAS DataBase Reference)
• NIST Chemistry Reference: Acetylferrocene(1271-55-2)
• EPA Substance Registry System: Acetylferrocene(1271-55-2)

Safety Data

• Hazard Codes: T+
• Statements: 28
• Safety Statements: 28-36/37-45-28A-1
• RIDADR: UN 2811 6.1/PG 2
• WGK Germany: 3
• RTECS: OB3700000
• F: 10
• TSCA: Yes
• HazardClass: 6.1
• PackingGroup: II
• Hazardous Substances Data: 1271-55-2(Hazardous Substances Data)

Usage

Chemical Properties

orange crystalline powder

Uses

1-Acetylferrocene was originally used in military or space field as an additive in rocket propellant, to promote the burning rate. Its ferrocenyl derivative has wide applications to biological and medical fields such as ferrocene-modified beta-lactam because of its physiological activity of anti-malarial, anti-tumor, bactericidal, anti-inflammatory, treatment of anemia, inhibition of enzymatic activity and so on by virtue of its unique structure and diverse properties.

Safety Profile

Poison by ocular and intravenous routes. A flammable liquid. When heated to decomposition it emits acrid smoke and irritating fumes.

Purification Methods

Orange-red crystals are obtained when it is recrystallised from isooctane or *C6H6, and then sublimed at 100o/1mm. The oxime has m 167-170o (from Et2O or aqueous EtOH). The semicarbazone has m 198-201o (from EtOH). [Richmond & Freiser J Am Chem Soc 77 2022 1955, Weinmayer J Am Chem Soc 77 3009 1955, Broadhead et al. J Chem Soc 650 1958, Beilstein 16 IV 1798.]

InChI:InChI=1/C7H8O/c1-6(8)7-4-2-3-5-7/h2-5,7H,1H3

Upstream product

• 127155-15-1 1,3-Benzenedicarboxylic acid, polymer with decanedioic acid, dimethyl 1,4-benzenedicarboxylate, 2,2-dimethyl-1,3-propanediol, 1,2-ethanediol and 2,2-oxybisethanol 
• 1271-54-1 DIBENZENECHROMIUM 
• 127154-03-4 N-(cyclopropylmethyl)-6,14-endo-etheno-7-(3-carboxy-3-n-butenyl)tetrahydronororipavine gamma-lactone 
• 127153-87-1 1-(1,2,2-trimethylindan-1-yl)ethanone 
• 127153-86-0 (3E)-4-(3a,4,5,6,7,7a-hexahydro-1H-4,7-methanoinden-5-yl)-3-methylbut-3-en-2-ol 
• 127153-83-7 Nitric acid, reaction products with cyclododecanol and cyclododecanone, by-products from, high-boiling fraction, Me esters 
• 127153-81-5 Antimony oxide (Sb2O3), reaction products with talc 
• 1271530-46-1 2-[Isopropyl-(3-nitro-benzyl)-aMino]-ethanol 
• 127152-64-1 5-(4-BROMO-BENZYL)-2H-TETRAZOLE 
• 127152-00-5 Ethanamine, 2-(2-thiazolylthio)- 
• 1271-51-8 Vinylferrocene 
• 1271-48-3 1,1'-FERROCENEDICARBOXALDEHYDE 
• 12714-78-2 Y 105 
• 127147-73-3 benzene,formaldehyde,urea 

Downstream Products

• 1273-89-8 Ethylferrocene 
• 1271-47-2 ETHYNYLFERROCENE 
• 1271-51-8 Vinylferrocene 

Recommend Products

• 102-54-5  ferrocene 
• 506-96-7  Acetyl bromide 
• 17333-74-3  2-methylbenzene diazonium 
• 108-30-5  succinic acid anhydride 
• 94619-64-4  bis(ferrocenyl acetylide)mercury 
• 1277-49-2  1-ferrocenylethanol 
• 7732-18-5  water 
• 1271-51-8  vinyl ferrocene 
• 16853-85-3  lithium aluminium tetrahydride 
• 75-36-5  acetyl chloride 
• 1273-94-5  1,1'-diacetylferrocene 
• 7647-01-0  hydrogenchloride 
• 56-23-5  tetrachloromethane 
• 591-51-5  phenyllithium 

Related news

The preparation of (5-aryl-3-isoxazolyl)-ferrocenes from dilithiated Acetylferrocene (cas 1271-55-2) oxime and aromatic esters08/18/2019

Acetylferrocene oxime was dilithiated with excess lithium diisopropylamide and the resulting C(α),O-dilithiated oxime was condensed at the carbanion-type center with aromatic esters to yield C-acylated intermediates that were quenched and acid-cyclined to the (5-aryl-3-isoxazolyl)-ferrocenes (i...detailed

Synthesis and structures of Acetylferrocene (cas 1271-55-2) thiosemicarbazones and their dimethylthallium(III) complexes, which have four- or five-membered chelate rings08/17/2019

Five thiosemicarbazones HLn=Fc(Me)C(2)N(3)N(2)(H)C(1)(S)N(1)R1R2 (Fc=ferrocenyl) were prepared by condensing acetylferrocene with thiosemicarbazide or 4-substituted thiosemicarbazides: acetylferrocene thiosemicarbazone (HL1), acetylferrocene 1N-methylthiosemicarbazone (HL2), acetylferroc...detailed

Chelates of Acetylferrocene (cas 1271-55-2) benzoylhydrazone with lanthanides08/15/2019

The chelates, Ln(HL)2Cl3·nH2O of acetylferrocene benzoylhydrazone with 15 lanthanide(III) metals have been prepared and characterized by elemental analysis, IR, UV, molar conductance, TG and DTA. It was found that the ligand coordinates to the central ions in the keto form, and some chloride io...detailed

Evaluation of diesel fuel-biodiesel blends with palladium and Acetylferrocene (cas 1271-55-2) based additives in a diesel engine08/11/2019

Influence of biodiesel-diesel fuel blends with acetylferrocene and palladium based additives on diesel engine performance and emissions were studied experimentally. The additives were dosed into the blend fuels as 25 ppm. Bis-[N,N-dimethyl-N′-2-chlorobenzoylthioureato] palladium (II), PdL2 was ...detailed

Highly selective synthesis of Acetylferrocene (cas 1271-55-2) by acylation of ferrocene over zeolites08/10/2019

Zeolites with different structure and concentration of acid sites were investigated in a liquid phase acylation of ferrocene with acetic anhydride. It was found that the conversion of ferrocene increased in the order: medium pore zeolitesdetailed

Solubilities of ferrocene and Acetylferrocene (cas 1271-55-2) in supercritical carbon dioxide08/09/2019

In this work, the solubilities of ferrocene and acetylferrocene in supercritical carbon dioxide (scCO2) were measured using an analytical method in a quasi-flow apparatus. High-performance liquid chromatography was applied through an online sampling procedure to determine the concentration of fe...detailed