5116-22-3 Usage
Uses
Used in Biological Studies:
5-Methoxymethyl-2'-deoxyuridine is used as a research tool in biological studies for understanding the synthesis and mechanisms of nucleoside analogs. Its unique structure allows researchers to investigate its interactions with cellular machinery and its potential effects on biological processes.
Used in Antimicrobial Research:
In the field of antimicrobial research, 5-Methoxymethyl-2'-deoxyuridine is utilized for its in vitro antimycobacterial activity against Mycobacterium species, which are responsible for tuberculosis and other related diseases. Its ability to inhibit the growth of these pathogens makes it a promising candidate for the development of new antitubercular drugs.
Used in Medicinal Chemistry:
5-Methoxymethyl-2'-deoxyuridine is also employed in medicinal chemistry as a starting material or a building block for the synthesis of novel nucleoside analogs with potential therapeutic applications. Its unique structural features can be exploited to design new molecules with improved pharmacological properties, such as enhanced selectivity, potency, and reduced toxicity.
Used in Drug Development:
In the pharmaceutical industry, 5-Methoxymethyl-2'-deoxyuridine serves as a key component in the development of new drugs targeting various diseases, including viral infections and cancer. Its incorporation into drug candidates can lead to the discovery of more effective treatments with fewer side effects.
Overall, 5-Methoxymethyl-2'-deoxyuridine is a versatile compound with a wide range of applications in scientific research, drug development, and medical treatments. Its unique properties and potential uses make it an important subject of study for researchers and pharmaceutical companies alike.
Check Digit Verification of cas no
The CAS Registry Mumber 5116-22-3 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,1,1 and 6 respectively; the second part has 2 digits, 2 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 5116-22:
(6*5)+(5*1)+(4*1)+(3*6)+(2*2)+(1*2)=63
63 % 10 = 3
So 5116-22-3 is a valid CAS Registry Number.
5116-22-3Relevant academic research and scientific papers
O-glycoside orientation is an essential aspect of base J recognition by the kinetoplastid DNA-binding protein JBP1
Grover, Rajesh K.,Pond, Stephanie J. K.,Cui, Qizhi,Subramaniam, Prem,Case, David A.,Millar, David P.,Wentworth Jr., Paul
, p. 2839 - 2843 (2008/02/14)
A binding edge? Comparison of dissociation constants and molecular-dynamics snapshots of a panel of synthetic telomeric double-stranded DNA sequences containing HMdU O-glycosides has revealed that the DNA-binding protein of kinetoplastids, such as Leishma
A facile one-pot synthesis of 2,3'-anhydro-2'-deoxyuridines via 3'-O-imidazolylsulfonates
No,Dong Seong Shin,Bok Ju Song,Ahn,Ha
, p. 3873 - 3882 (2007/10/03)
Continued interests in the novel synthetic methods of the pivotal compound, 2,3'-anhydro-2'-deoxyribonucleosides (7) uncovered a facile one-pot conversion of 5 with 1,1'-sulfonyldiimidazole in basic conditions to 7 with almost quantitative yields (91-99%).
