51209-20-2Relevant academic research and scientific papers
Process for preparing hyperpolarized substrates and method for MRI
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Page/Page column 35, (2017/08/01)
The present invention generally relates to a process for the preparation of aqueous solutions of hyperpolarized molecules ready for use in in-vivo MR diagnostic imaging, the use thereof as MRI contrast agent in investigation methods for producing diagnostic MR images of a human or non-human animal body organ, region or tissue.
Sulfonamide derivatives
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Page 8-12, (2010/02/05)
The present invention relates to a compound of formula (I) or a pharmaceutically acceptable salt thereof which is useful for the treatment of conditions associated with glutamate hypofunction, such as psychiatric and neurological disorders.
Enzymatic Production of L-Malate from Maleate by Alcaligenes sp.
Kimura, Takuhei,Kawabata, Yasuro,Sato, Eiji
, p. 89 - 94 (2007/10/02)
Alcaligenes sp.T501, which has the ability to produce L-malate from maleate at a concentration of 20percent in a molar yield of 98.4percent was isolated from soil.Analysis of the reaction mixture components suggested that maleate was converted to L-malate via fumarate through the action of maleate isomerase and fumarase.These two enzymes were constitutively found in the cells regardless of the carbon source in the medium.The enzyme reaction was significantly enhanced by adding 2-mercaptoethanol, but was not affected by glutathione or L-cysteine.
