51209-87-1Relevant academic research and scientific papers
Acid catalysed reaction of estrones with neopentyl glycol under forced conditions
Oliveira, Cristina,Morais, Goreti Ribeiro,Imai, Masao,Inohae, Eiko,Yamamoto, Chishou,Mataka, Shuntaro,Thiemann, Thies
experimental part, p. 158 - 162 (2010/08/06)
Upon reaction with an excess of 2,2-dimethylpropane-1,3-diol (neopentyl glycol) under acid catalysis, estrones form 17-O-[2',2'-dimethyl-2'-(5", 5"-dimethyl-1",3"-dioxanyl)ethyl] substituted estra-3,17β-diols. The reaction represents a formal reduction of a keto function under acidic conditions in the absence of a metal.
