512176-79-3

Basic information

• Product Name: benzyl 3-oxo-2-phenylbutanoate
• Synonyms: benzyl 3-oxo-2-phenylbutanoate
• CAS NO: 512176-79-3
• Molecular Weight: 268.312
• Mol File: 512176-79-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: benzyl 3-oxo-2-phenylbutanoate(CAS DataBase Reference)
• NIST Chemistry Reference: benzyl 3-oxo-2-phenylbutanoate(512176-79-3)
• EPA Substance Registry System: benzyl 3-oxo-2-phenylbutanoate(512176-79-3)

Safety Data

• Hazardous Substances Data: 512176-79-3(Hazardous Substances Data)

Upstream product

• 102-16-9 benzyl 2-phenylacetate 
• 108-24-7 acetic anhydride 
• 87769-42-4 5-phenyl-2,2,6-trimethyl-2h,4h-1,3-dioxin-4-one 
• 100-51-6 benzyl alcohol 
• 100-39-0 benzyl bromide 
• 103-82-2 phenylacetic acid 

Downstream Products

• 512176-91-9 benzyl 2-acetyl-2-phenylpropanoate 
• 79120-96-0 (R)-(-)-3-phenylbutan-2-one 
• 23406-52-2 (S)-2-phenylpentan-3-one 
• 7782-26-5 (R)-2-Phenylpropionic acid 
• 7782-24-3 (S)-2-Phenylpropionic acid 

Relevant articles and documents

Highly efficient palladium-catalyzed Suzuki-Miyaura reactions of potassium aryltrifluoroborates with 5-iodo-1,3-dioxin-4-ones in water: an approach to α-aryl-β-ketoesters

The high efficient palladium-catalyzed Suzuki-Miyaura reactions of potassium aryltrifluoroborates 3 with 5-iodo-1,3-dioxin-4-ones 2a-b in water as only solvent in the presence of n-Bu4NOH as base is reported. The respective 5-aryl-1,3-dioxin-4-ones 4a-n were obtained in good to excellent yields. The catalyst system provides high efficiency at low load using electronically diverse coupling partners. The obtained 2,2,6-trimethyl-5-aryl-1,3-dioxin-4-ones were transformed into corresponding α-aryl-β-ketoesters 6 by reaction with an alcohol in the absence of solvent.