51219-00-2Relevant articles and documents
Compound herbicide based on dichloro quinolinic acid
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Paragraph 0021; 0031; 0039; 0041; 0049; 0051; 0059, (2021/11/21)
The invention discloses a compound herbicide based on quinclorac, which comprises 20 - 30 parts of quinclorac. Dichloromethane 3-8 parts, synergist 10 - 20 parts, wetting agent 1.5 - 4.5 parts, dispersing agent 1-3 parts, defoaming agent 0.5 - 2.5 parts and water 50 - 70 parts. The synergist inhibits the growth of cells by hindering the synthesis of the protein, and the sprouts of monocotyledonous plants are obtained through young buds of plants. The lower endoderm of the dicotyledonous plant is absorbed and conducted upwards, the seeds and roots absorb conduction, the absorption amount is low, the conduction speed is slow, the growth of young buds and roots is inhibited.
Method for asymmetric reductive amination based on fructose-derived chiral monodentate phosphite ligand ketone
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Paragraph 0085-0089, (2020/07/06)
The invention discloses a method for preparing chiral amine based on asymmetric reductive amination of fructose-derived chiral monodentate phosphite ligand ketone, which comprises the following steps:reacting fructose-derived chiral monodentate phosphite ligand with a metal iridium precursor to prepare a complex in situ as a catalyst, and carrying out direct asymmetric reductive amination on ketone and amine to prepare chiral amine. The ligand disclosed by the invention is simple to prepare, the catalyst dosage is low, the operation is simple and convenient, continuous operation can be realized, the method is suitable for large-scale preparation of chiral amine, the enantiomeric excess value of the product reaches 80% or above, and the requirement of serving as a pesticide intermediate can be met. The method disclosed by the invention has a relatively good result when 2-ethyl-6-methylaniline/catalyst (S/C) is 10000 during synthesis of an s-metolachlor intermediate, the yield is 95%, the enantioselectivity is 85%, and the method has very good industrial practicability.
Chiral mono-dentate phosphine ligand asymmetric hydrogenation imine method based on D - mannitol (by machine translation)
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Paragraph 0079-0083, (2020/07/06)
The chiral mono-dentate phosphine ligand derived based on D - mannide is prepared by reacting D - mannitol-derived chiral mono-dentate phosphine ligand and a metal iridium precursor in situ to prepare the complex as a catalyst, and imine asymmetric hydrogenation to prepare chiral amine. Suitable catalyst amounts (in terms of mol) are: The raw material imine/catalyst (S/C) is equal 100 - 10000. The ligand is simple to prepare, low in catalyst consumption and simple and convenient to operate, can realize continuous operation, is suitable for large-scale preparation of chiral amine, ee value of the product reaches 75percent or more, and can meet the requirement of a pesticide intermediate. The method has good results for the synthesis of the metolachlor intermediate, and has good industrial applicability. (by machine translation)