51219-00-2

Usage

Uses

Used in Agricultural Industry:
2-ethyl-N-(2-methoxyisopropyl)-6-methylaniline is used as an insecticide and acaricide for controlling a wide range of insect and mite pests in agricultural settings. It works by inhibiting the activity of acetylcholinesterase, an enzyme crucial for nerve impulse transmission, which disrupts the nervous system of target organisms, leading to paralysis and death. This broad-spectrum activity makes it a valuable tool for pest control in agriculture.

Upstream product

• 24549-06-2 6-ethyl-o-toluidine 
• 23652-67-7 ethyl (Z)-β-acetylaminobut-2-enoate 
• 132034-47-0 N-(2-ethyl-6-methylphenyl)-N-(1'-methoxymethyl)-ethylidene-amine 
• 5878-19-3 Methoxyacetone 
• 118604-68-5 N-(2’-methyl-6’-ethyl-phenyl)-N-1-(methoxymethyl)ethylimine 
• 85385-06-4 2,6-dimethylphenyl-1'-methyl-2'-methoxyethyl-imine 
• 22461-48-9 2-Bromo-1-methoxypropane 
• 74-88-4 methyl iodide 

Downstream Products

• 68545-14-2 N-(2-Ethyl-6-methyl-phenyl)-3-methoxy-N-(2-methoxy-1-methyl-ethyl)-propionamide 
• 51218-45-2 2-chloro-6'-ethyl-N-(2-methoxy-1-methylethyl)acet-o-toluidide 
• 178961-20-1 (aRS,1'R)-(+)-N-(1'-Methyl-2'-methoxyethyl)-N-chloracetyl-2-ethyl-6-methylanilin 
• 87392-12-9 (S)-metolachlor 
• 343629-68-5 N-(2-ethyl-6-methylphenyl)-N-(1-methoxypropan-2-yl)benzamide 
• 126404-32-8 3-[(2-Ethyl-6-methyl-phenyl)-(2-methoxy-1-methyl-ethyl)-carbamoyl]-but-3-enoic acid methyl ester 

Relevant academic research and scientific papers

Compound herbicide based on dichloro quinolinic acid

The invention discloses a compound herbicide based on quinclorac, which comprises 20 - 30 parts of quinclorac. Dichloromethane 3-8 parts, synergist 10 - 20 parts, wetting agent 1.5 - 4.5 parts, dispersing agent 1-3 parts, defoaming agent 0.5 - 2.5 parts and water 50 - 70 parts. The synergist inhibits the growth of cells by hindering the synthesis of the protein, and the sprouts of monocotyledonous plants are obtained through young buds of plants. The lower endoderm of the dicotyledonous plant is absorbed and conducted upwards, the seeds and roots absorb conduction, the absorption amount is low, the conduction speed is slow, the growth of young buds and roots is inhibited.

Method for asymmetric reductive amination of ketone based on fructose-derived pyridinol chiral ligand

The invention discloses a method for asymmetric reductive amination of ketone based on a fructose-derived pyridinol chiral ligand, which comprises the following steps: reacting a fructose-derived pyridinol chiral ligand with a metal iridium precursor to prepare a complex in situ as a catalyst, and carrying out direct asymmetric reductive amination on ketone and amine to prepare chiral amine. The ligand disclosed by the invention is simple to prepare, the catalyst dosage is low, the operation is simple and convenient, continuous operation can be realized, the method is suitable for large-scalepreparation of chiral amine, the enantiomeric excess value of the product reaches 70% or above, and the requirement of serving as a pesticide intermediate can be met. The method has a good result whenthe 2-ethyl-6-methylaniline/catalyst (S/C) is 10000 during synthesis of an s-metolachlor intermediate, the yield is 95%, the enantioselectivity is 75%, and the method has good industrial practicability.

Method for asymmetric reductive amination based on fructose-derived chiral monodentate phosphite ligand ketone

The invention discloses a method for preparing chiral amine based on asymmetric reductive amination of fructose-derived chiral monodentate phosphite ligand ketone, which comprises the following steps:reacting fructose-derived chiral monodentate phosphite ligand with a metal iridium precursor to prepare a complex in situ as a catalyst, and carrying out direct asymmetric reductive amination on ketone and amine to prepare chiral amine. The ligand disclosed by the invention is simple to prepare, the catalyst dosage is low, the operation is simple and convenient, continuous operation can be realized, the method is suitable for large-scale preparation of chiral amine, the enantiomeric excess value of the product reaches 80% or above, and the requirement of serving as a pesticide intermediate can be met. The method disclosed by the invention has a relatively good result when 2-ethyl-6-methylaniline/catalyst (S/C) is 10000 during synthesis of an s-metolachlor intermediate, the yield is 95%, the enantioselectivity is 85%, and the method has very good industrial practicability.

Method for preparing chiral amine through asymmetric hydrogenation based on glucose-derived monodentate phosphite ligand

The invention discloses a method for preparing chiral amine through asymmetric hydrogenation based on a glucose-derived monodentate phosphite ligand. The method comprises the following steps: reactinga chiral glucose-derived monodentate phosphite ligand with a metal iridium precursor to prepare a complex in situ as a catalyst, and carrying out asymmetric hydrogenation on imine to prepare chiral amine. The proper catalyst dosage (by mole) is as follows: the raw material imine/catalyst (S/C) is equal to 100-500,000. The ligand disclosed by the invention is simple to prepare, the catalyst dosageis low, the operation is simple and convenient, continuous operation can be realized, the method is suitable for large-scale preparation of chiral amine, the enantiomeric excess (ee value) of the product reaches 70% or above, and the requirement of serving as a pesticide intermediate can be met. According to the method, a good result is obtained for synthesis of an s-metolachlor intermediate, andthe method has good industrial practicability.

Chiral mono-dentate phosphine ligand asymmetric hydrogenation imine method based on D - mannitol (by machine translation)

The chiral mono-dentate phosphine ligand derived based on D - mannide is prepared by reacting D - mannitol-derived chiral mono-dentate phosphine ligand and a metal iridium precursor in situ to prepare the complex as a catalyst, and imine asymmetric hydrogenation to prepare chiral amine. Suitable catalyst amounts (in terms of mol) are: The raw material imine/catalyst (S/C) is equal 100 - 10000. The ligand is simple to prepare, low in catalyst consumption and simple and convenient to operate, can realize continuous operation, is suitable for large-scale preparation of chiral amine, ee value of the product reaches 75percent or more, and can meet the requirement of a pesticide intermediate. The method has good results for the synthesis of the metolachlor intermediate, and has good industrial applicability. (by machine translation)

Asymmetric reductive amination method for catalyzing ketones with iridium chiral phosphine-aminophosphine ligand system

The invention discloses an asymmetric reductive amination method for catalyzing ketones with an iridium chiral phosphine-aminophosphine ligand system, which comprises the following steps: reacting a chiral phosphine-aminophosphine ligand with a metal iridium precursor to prepare a complex in situ as a catalyst, and catalyzing direct asymmetric reductive amination of a ketone and an amine to prepare a chiral amine. The ligand disclosed by the invention is simple to prepare, catalyst dosage is, operation is simple and convenient, the method is capable of realizing continuous operation and is suitable for large-scale preparation of chiral amines, the enantiomeric excess value of the product reaches 80% or above, and the requirement of serving as a pesticide intermediate can be met. The method has a good result when the S/C (2-ethyl-6-methylaniline/catalyst) rate is 500,000 during synthesis of the s-metolachlor intermediate, the yield is 95%, the enantioselectivity is 85%, and the methodhas good industrial practicability.

Iridium/chiral phosphite ester-pyridine catalyzed imine asymmetric hydrogenation method

The invention discloses a method for catalyzing asymmetric hydrogenation of imines with iridium/chiral phosphite ester-pyridine, which comprises the following steps: reacting a chiral phosphite ester-pyridine (P, N) ligand with a metal iridium precursor to prepare a complex in situ as a catalyst, and carrying out asymmetric hydrogenation on an imine to prepare a chiral amine. The ligand is simpleto prepare; catalyst dosage is low, operation is simple, continuous operation can be realized, the preparation method is simple in process and suitable for large-scale preparation of chiral amines, the enantiomeric excess value of the product reaches 85% or above, the preparation method is excellent in effect in result when the S/C (2-ethyl-6-methylaniline/catalyst) rate is 500,000 during synthesis of the s-metolachlor intermediate, the yield is 95%, the enantioselectivity is 91%, and good industrial practicability is achieved.

Asymmetric reductive amination method of ketone (by machine translation)

The method takes the chiral tetrahydronaphthalene skeleton phosphine-phosphonamide ligand and, the metal iridium precursor, to prepare a complex, and the method takes the chiral tetralin amine skeleton phosphine-phosphonamide ligand, and the, metal iridium precursor in situ . 80%, 2 -(S/C) 500000, 95%, 80%. (by machine translation)

Asymmetric reductive amination method of iridium catalytic ketone (by machine translation)

The method takes the chiral ferrocene skeleton phosphine-phosphonamide ligand to react, in situ with the metal iridium precursor, to prepare the chiral amine, and/the method is simple 95% and convenient, to operate . 80%, 2 - (S/C) 500000, 81%. (by machine translation)

Method for preparing chiral amine through asymmetric reductive amination of ketone

The invention discloses a method for preparing a chiral amine by asymmetric reductive amination of a ketone, which comprises the following steps: reacting a chiral phosphine-phosphoramidite ligand with a metal iridium precursor to prepare a complex in situ as a catalyst, and carrying out direct asymmetric reductive amination on the ketone and an amine to prepare chiral amine. The ligand disclosedby the invention is simple to prepare, low in catalyst dosage, simple and convenient to operate, capable of realizing continuous operation and suitable for large-scale preparation of chiral amine, theenantiomeric excess value of the product reaches 80% or above, and the requirement of serving as a pesticide intermediate can be met. The method has a good result when the S/C (2-ethyl-6-methylaniline/catalyst) ratio is 500,000 during synthesis of the s-metolachlor intermediate, the yield is 95%, the enantioselectivity is 80%, and the method has good industrial practicability.