51219-20-6

Basic information

• Product Name: Carbamic acid, [[3-[[(1,1-dimethylethoxy)carbonyl]amino]-2-oxo-1-piperidinyl]iminometh yl]-, phenylmethyl ester, (S)-
• CAS NO: 51219-20-6
• Molecular Formula: C19H26N4O5
• Molecular Weight: 390.43400
• Mol File: 51219-20-6.mol
• Article Data: 4

Chemical Properties

• Melting Point: 164-166 °C
• Density: 1.27±0.1 g/cm3(Predicted)
• CAS DataBase Reference: Carbamic acid, [[3-[[(1,1-dimethylethoxy)carbonyl]amino]-2-oxo-1-piperidinyl]iminometh yl]-, phenylmethyl ester, (S)-(CAS DataBase Reference)
• NIST Chemistry Reference: Carbamic acid, [[3-[[(1,1-dimethylethoxy)carbonyl]amino]-2-oxo-1-piperidinyl]iminometh yl]-, phenylmethyl ester, (S)-(51219-20-6)
• EPA Substance Registry System: Carbamic acid, [[3-[[(1,1-dimethylethoxy)carbonyl]amino]-2-oxo-1-piperidinyl]iminometh yl]-, phenylmethyl ester, (S)-(51219-20-6)

Safety Data

• Hazardous Substances Data: 51219-20-6(Hazardous Substances Data)

Upstream product

• 501-53-1 benzyl chloroformate 
• 13726-76-6 t-butyloxycarbonyl-L-arginine 
• 51219-18-2 Boc-Arg(Cbz)-OH 
• 51219-18-2 N⁷-<(benzyloxy)carbonyl>-N²-<(tert-butoxy)carbonyl>-L-arginine 
• 74-79-3 L-arginine 
• 24424-99-5 di-tert-butyl dicarbonate 
• 35897-34-8 N^α-t-butoxycarbonyl-arginine hydrochloride 

Downstream Products

• 180003-04-7 C₂₆H₃₁N₅O₅S 
• 180152-33-4 C₂₁H₂₃N₅O₃S 
• 84052-82-4 [1-Amino-1-((S)-3-amino-2-oxo-piperidin-1-yl)-meth-(E)-ylidene]-carbamic acid benzyl ester 

Relevant articles and documents

Process for preparing peptidyl heterocyclic ketone derivatives

The present invention relates to novel processes for the preparation of peptidyl heterocyclic ketones of the general formula (I) wherein all variables are as herein defined. The present invention further relates to novel pharmaceutical salts and processes

Synthesis and structure-activity relationship of potent bicyclic lactam thrombin inhibitors

A simple and versatile method for preparation of (D)-Phe-Pro peptidomimetic bicyclic thiazolidine lactams is presented. These bicyclic lactams have chemical diversity α to the lactam carbonyl and, when linked to electrophilic arginines, provide potent thrombin inhibitors.