51234-94-7

Usage

Antioxidant properties

It helps neutralize harmful free radicals, potentially benefiting skincare and cosmetic products.

Anti-inflammatory properties

Coumarin may help reduce inflammation, making it a potential ingredient in skincare products.

Upstream product

• 62143-66-2 1-benzoylamino-2-benzoyloxy-4-methyl-benzene 
• 51234-51-6 6-bromomethyl-2-phenyl-benzooxazole 
• 3743-11-1 N-(2-hydroxy-4-methylphenyl)benzamide 
• 98-88-4 benzoyl chloride 
• 62143-69-5 2-phenyl-6-benzoxazolylacetic acid 
• 62143-68-4 (2-phenyl-benzooxazol-6-yl)-acetonitrile 
• 51234-52-7 (2-phenyl-benzooxazol-6-yl)-acetic acid ethyl ester 

Relevant academic research and scientific papers

IMIDAZOLE DERIVATIVES AS IDO INHIBITORS

Presently provided are IDO inhibitors of general formulae (VII), (VIII) as shown below and pharmaceutical compositions thereof, useful for modulating an activity of indoleamine 2,3-dioxygenase; treating indoleamine 2,3-dioxygenase (IDO) mediated immunosuppression; treating a medical conditions that benefit from the inhibition of enzymatic activity of indoleamine-2,3-dioxygenase; enhancing the effectiveness of an anti-cancer treatment comprising administering an anti-cancer agent; treating tumor-specific immunosuppression associated with cancer; and treating immunosupression associated with an infectious disease.

Benzoxazole derivatives in treating inflammation, pain and fever

The invention provides novel 5- and 6-benzoxazolyl alkanoic acids, optionally substituted in the 2-position, and derivatives thereof which possess anti-inflammatory, anti-pyretic and analgesic activity. Also provided is a process for preparing such compounds by cyclising an appropriately substituted o-aminophenol and, if necessary, converting the resultant benzoxazole to the desired compound.