51339-39-0 Usage
Uses
Used in Organic Synthesis:
(3-bromo-5-nitrophenyl)phenylmethanone is used as a building block in the production of various pharmaceuticals and agrochemicals. Its chemical structure allows for the creation of a wide range of compounds with different therapeutic and pesticidal properties.
Used in Biological Research:
(3-bromo-5-nitrophenyl)phenylmethanone has been studied for its potential biological activities, including anti-inflammatory and antibacterial properties. Its ability to exhibit these effects makes it a candidate for further research in the development of new treatments for inflammation and bacterial infections.
Used in Bioimaging Applications:
(3-bromo-5-nitrophenyl)phenylmethanone has been investigated for its potential use as a fluorescent probe in bioimaging. Its optical properties could be harnessed to enhance the visualization of biological processes and structures, contributing to advancements in medical diagnostics and research.
Used in Chemical Research:
As a member of the aryl ketone class, (3-bromo-5-nitrophenyl)phenylmethanone may also be utilized in chemical research to understand the behavior of similar compounds and their interactions with other molecules, which could lead to the discovery of new chemical reactions and applications.
It is crucial to handle (3-bromo-5-nitrophenyl)phenylmethanone with care, as it is toxic and can cause skin and eye irritation upon contact. Proper safety measures should be taken during its use in any application.
Check Digit Verification of cas no
The CAS Registry Mumber 51339-39-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,1,3,3 and 9 respectively; the second part has 2 digits, 3 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 51339-39:
(7*5)+(6*1)+(5*3)+(4*3)+(3*9)+(2*3)+(1*9)=110
110 % 10 = 0
So 51339-39-0 is a valid CAS Registry Number.
51339-39-0Relevant academic research and scientific papers
Targeting epigenetic reader and eraser: Rational design, synthesis and in vitro evaluation of dimethylisoxazoles derivatives as BRD4/HDAC dual inhibitors
Zhang, Zhimin,Hou, Shaohua,Chen, Hongli,Ran, Ting,Jiang, Fei,Bian, Yuanyuan,Zhang, Dewei,Zhi, Yanle,Wang, Lu,Zhang, Li,Li, Hongmei,Zhang, Yanmin,Tang, Weifang,Lu, Tao,Chen, Yadong
supporting information, p. 2931 - 2935 (2016/06/09)
The bromodomain protein module and histone deacetylase (HDAC), which recognize and remove acetylated lysine, respectively, have emerged as important epigenetic therapeutic targets in cancer treatments. Herein we presented a novel design approach for cancer drug development by combination of bromodomain and HDAC inhibitory activity in one molecule. The designed compounds were synthesized which showed inhibitory activity against bromodomain 4 and HDAC1. The representative dual bromodomain/HDAC inhibitors, compound 11 and 12, showed potent antiproliferative activities against human leukaemia cell line K562 and MV4-11 in cellular assays. This work may lay the foundation for developing dual bromodomain/HDAC inhibitors as potential anticancer therapeutics.
