6307-87-5

Basic information

• Product Name: Methyl 3-bromo-5-nitrobenzoate
• Synonyms: Methyl 3-bromo-5-nitrobenzoate;Methyl 3-bromo-5-nitrobenzoate 98%;Methyl3-bromo-5-nitrobenzoate98%;3-Bromo-5-nitro-benzoic acid methyl ester
• CAS NO: 6307-87-5
• Molecular Formula: C₈H₆BrNO₄
• Molecular Weight: 260.04154
• Product Categories: blocks;Bromides;Carboxes
• Mol File: 6307-87-5.mol
• Article Data: 23

Chemical Properties

• Melting Point: 70 °C(Solv: ethanol (64-17-5))
• Boiling Point: 326.042 °C at 760 mmHg
• Flash Point: 150.985 °C
• Appearance: /
• Density: 1.674 g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.588
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: Methyl 3-bromo-5-nitrobenzoate(CAS DataBase Reference)
• NIST Chemistry Reference: Methyl 3-bromo-5-nitrobenzoate(6307-87-5)
• EPA Substance Registry System: Methyl 3-bromo-5-nitrobenzoate(6307-87-5)

Safety Data

• Hazard Codes: Xi
• Hazardous Substances Data: 6307-87-5(Hazardous Substances Data)

Usage

General Description

Methyl 3-bromo-5-nitrobenzoate is a chemical compound with the molecular formula C8H6BrNO4. It is a nitro-substituted aromatic ester, containing a nitro group and a bromine atom attached to a benzene ring. Methyl 3-bromo-5-nitrobenzoate is commonly used as a building block in organic synthesis and medicinal chemistry as it serves as a precursor for the synthesis of various pharmaceuticals and agrochemicals. Additionally, its distinctive chemical structure and reactivity make it a valuable intermediate in the production of dyes, pigments, and other fine chemicals. Overall, methyl 3-bromo-5-nitrobenzoate plays a crucial role in the development and production of a wide range of important chemical compounds.

InChI:InChI=1/C8H6BrNO4/c1-14-8(11)5-2-6(9)4-7(3-5)10(12)13/h2-4H,1H3

Upstream product

• 618-95-1 methyl 3-nitrobenzoate 
• 67-56-1 methanol 
• 6307-83-1 3-bromo-5-nitro-benzoic acid 
• 618-89-3 methyl 3-bromobenzoate 
• 1025718-78-8 methyl 3-bromo-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate 
• 121-92-6 3-nitrobenzoic acid 
• 74-88-4 methyl iodide 

Downstream Products

• 6307-83-1 3-bromo-5-nitro-benzoic acid 
• 706791-83-5 3-amino-5-bromobenzoic acid methyl ester 
• 398119-24-9 2-[2-(2-methoxyethoxy)ethoxy]ethyl 5-bromo-3-nitrobenzoate 
• 102153-77-5 3-(dihydroxyphosphoryl)-5-nitrobenzoic acid 
• 1426520-50-4 methyl 3-amino-5-(diethoxyphosphoryl)benzoate 
• 1068437-86-4 3-amino-5-(dihydroxyphosphoryl)benzoic acid 
• 1426520-49-1 methyl 3-(diisopropyloxyphosphoryl)-5-nitrobenzoate 
• 1610566-96-5 methyl 3-(2,7-diphenylheptylamino)-5-nitrobenzoate 
• 1610566-94-3 methyl 3-(4-(hexyloxycarbonyl)phenylamino)-5-nitrobenzoate 
• 1445786-28-6 3-((3-carbamoyl-7-(2,4-dimethoxypyrimidin-5-yl)quinolin-4-yl)amino)-5-(propylamino)benzoic acid 
• 1445790-28-2 methyl 3-(3-carbamoyl-7-chloro-6-(cyclopentylmethoxy)quinolin-4-ylamino)-5-cyclopentylbenzoate 
• 1445787-09-6 3-((3-carbamoyl-6-(cyclopentylmethoxy)-7-(2,4-dimethoxypyrimidin-5-yl)quinolin-4-yl)amino)-5-cyclopentylbenzoic acid 
• 1445790-24-8 methyl 3-((3-carbamoyl-6-(cyclobutylmethoxy)-7-(2,4-dimethoxypyrimidin-5-yl)quinolin-4-yl)amino)-5-cyclopentylbenzoate 
• 1445790-22-6 methyl 3-(3-carbamoyl-7-chloro-6-(cyclobutylmethoxy)quinolin-4-ylamino)-5-cyclopentylbenzoate 

Relevant articles and documents

POLYIMIDE-POLYARYLENE POLYMERS

Disclosed is a bis-imide compound comprising two or more aryl moieties substituted with ethynyl moieties and the two or more aryl moieties each having one or more polar substituents. Further disclosed is a polymer composition comprising a copolymer polymerized from a monomer mixture of (a) one or more first monomers comprising a bis-imide compound comprising two or more aryl moieties substituted with ethynyl moieties and the two or more aryl moieties each having one or more polar substituents; and (b) one or more second monomers comprising two or more cyclopentadienone moieties. The polymer compositions exhibit favorable properties for use in electronics and displays applications.

PROTEIN KINASE INHIBITORS FOR PROMOTING LIVER REGENERATION OR REDUCING OR PREVENTING HEPATOCYTE DEATH

The invention relates to compounds of formula (I) which are inhibitors of MKK4 (mitogen-activated protein kinase kinase 4) and their use in promoting liver regeneration or reducing or preventing hepatocyte death. The compounds selectively inhibit protein kinase MKK4 over protein kinases JNK and MKK7. (I), wherein R x, R y , R z and R zz are selected from: a) R x and R y are F and R z and R zz are H; b) R x, R y and R zz are independently halogen and R z is H; c) R x R z and R zz are independently halogen and R y is H; and d) R x R y and R z are independently halogen and R zz is H

Catalytic Direct Construction of Cyano-tetrazoles

Cyano-tetrazole is the first reported compound that bears four nitrogen atoms in a single five-membered ring. This unique molecular scaffold has long been ignored after its discovery in 1885, mainly attributed to the scarcity of available synthetic methods. Indeed, the most popular approach to tetrazoles (that is the cycloaddition reaction between nitriles and azides) has inevitably excluded the possibility of introducing valuable cyano groups to decorate the final heterocyclic cores. Here, we describe a completely different disconnection strategy to the long time-pursued cyano-tetrazoles via a simple, direct, and practical cycloaddition transformation between readily accessible aryl diazonium salts and diazoacetonitrile. This method provides both regioisomers of disubstituted tetrazoles from the same set of starting materials in a metal cation controlled fashion.