51374-71-1

Usage

InChI:InChI=1/C4H9O4P/c5-9(6)7-3-1-2-4-8-9/h1-4H2,(H,5,6)

Upstream product

• 10305-36-9 phosphoric acid mono-(4-hydroxy-butyl) ester 
• 538-75-0 dicyclohexyl-carbodiimide 
• 110-63-4 Butane-1,4-diol 
• 7191-26-6 2-phenoxy-[1,3,2]dioxaphosphepane 2-oxide 
• 18748-21-5 2-ethoxy-[1,3,2]dioxaphosphepane 2-oxide 
• 1498-51-7 ethyl phosphodichloridite 
• 85437-95-2 3-(2-Oxo-2λ⁵-[1,3,2]dioxaphosphepan-2-yloxy)-butan-2-one 
• 690652-91-6 2-benzyloxy-[1,3,2]dioxaphosphepane 2-oxide 

Relevant academic research and scientific papers

Controlled/living ring-opening polymerization of ε-caprolactone catalyzed by phosphoric acid

The bulk ring-opening polymerization (ROP) of ε-caprolactone (ε-CL) by various phosphoric acids using phenylmethanol as the initiator was conducted. 1,1'-bi-2-Naphthol (BINOL)-based phosphoric acid was found to be an effective organocatalyst for ROP leading to polyesters at 90°C. The overall conversion to poly(ε-caprolactone) was more than 96% and poly(ε-caprolactone) with Mw of 8400 and polydispersity index of 1.13 was obtained. 1H NMR spectra of oligomers demonstrated the quantitative incorporation of the protic initiator in the polymer chains and showed that transesterification reactions did not occur to a significant extent. The controlled polymerization was indicated by the linear relationships between the number- average molar mass and monomer conversion or monomer-to-initiator ratio. In addition, the present protocol provided an easy-to-handle, inexpensive and environmentally benign entry for the synthesis of biodegradable materials as well as polyesters for biomedical applications. Science China Press and Springer-Verlag Berlin Heidelberg 2012.

2,4-Dinitrophenol as an activating reagent in a facile preparation of cyclic phosphate triesters

2,4-Dinitrophenol was employed with benzyloxy-bis-(diisopropylamino) phosphine to synthesise the cyclic phosphate derivatives of a series of alkane diols (HO-(CH2)n-OH, n=2-6) in good isolated yields. Tetrazole and DNP were compared

A CONVENIENT SYNTHESIS OF 6-, 7-, AND 8-MEMBERED CYCLIC PHOSPHODIESTERS

1,3-, 1,4-, and 1,5-Alkanediols are converted into the corresponding 6-, 7-, and 8-membered cyclic phosphodiesters in a two-step procedure utilizing N-(1,2-dimethylethenylenedioxyphosphoryl)imidazole (2) as the sole phosphorylating reagent.