51384-17-9Relevant articles and documents
Copper-Mediated Intramolecular N-N Bond Coupling Using Cerium(IV) Sulfate as the Oxidant for the Synthesis of 5-Thio-Substituted 1,2,4-Triazoles
Kwak, Se Hun,Kim, Kang-Tae,Yoo, Hyun-Jeong,Gong, Young-Dae
, p. 3874 - 3880 (2015/12/18)
A method for copper(II)-mediated N-N bond formation of N-imidoylisothioureas has been developed for the synthesis of 1,2,4-triazoles. The reaction requires cerium(IV) sulfate as an oxidant and proceeds at room temperature. This approach provides access to a variety of substituted 1,2,4-triazoles.