514213-33-3Relevant academic research and scientific papers
Asymmetric oxidation of 3-alkyl-1,2-cyclopentanediones. Part 1: 3-Hydroxylation of 3-alkyl-1,2-cyclopentanediones
Paju, Anne,Kanger, Tonis,Pehk, Tonis,Mueuerisepp, Aleksander-Mati,Lopp, Margus
, p. 2439 - 2448 (2007/10/03)
3-Alkyl-1,2-cyclopentanediones undergo asymmetric 3-hydroxylation with the Sharpless Ti-complex resulting in enantiomeric 3-hydroxy carbonyl compounds with ee up to 95% in yields of 22-40%.
Asymmetric oxidation of 1,2-cyclopentanediones
Paju, Anne,Kanger, T?nis,Pehk, T?nis,Lopp, Margus
, p. 6883 - 6887 (2007/10/03)
Cyclic 3-alkyl-1,2-cyclopentanediones undergo a direct asymmetric oxidation with the DET/Ti(OiPr)4/ tBuOOH oxidative system, resulting in enantiomeric α-hydroxy compounds and ring-cleaved hydroxylated acids (lactones) up to 95% ee. (C) 2000 Elsevier Science Ltd.
