51431-52-8Relevant academic research and scientific papers
A novel catalytic activity of bismuth(III) salts in palladium(II)-catalyzed atom economical Michael-type hydroarylation of nitroalkenes with aryltin compounds
Ohe, Toshiyuki,Uemura, Sakae
, p. 1269 - 1271 (2002)
A novel catalytic effect of bismuth(III) salts such as BiCl3, Bi2O3, and Bi(NO3)3·5H2O has been disclosed in new palladium(II)-catalyzed Michael-type hydroarylation of nitroalkenes with aryltin compounds. The reaction is atom economical in the tin compounds and slightly fewer than four aryl groups of tetraaryltins can be transferred to the products.
Novel isoquinoline-oxazoline chiral ligand and preparation and application thereof (by machine translation)
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Paragraph 0104-0109, (2020/06/20)
The invention relates to a novel isoquinoline-oxazoline chiral ligand as well as preparation and application thereof. Substituted radicals R in the general formula1 And R2 The isoquinoline-oxazoline chiral ligand disclosed by the invention can be used as a ligand and a metal to form a complex or a composition for asymmetric catalysis, and particularly the asymmetric Michael addition of the isoquinoline-oxazoline ligand and the metal palladium can effectively catalyze the asymmetric Michael addition of boric acid and nitroolefin, and has excellent stereoselectivity. (by machine translation)
Multifunctional isoquinoline-oxazoline ligands of chemical and biological importance
Li, Wei,Wang, Guotong,Lai, Jixing,Li, Shengkun
supporting information, p. 5902 - 5905 (2019/05/27)
Multifunctional isoquinoline-oxazolines (MIQOXs) were conceived and synthesized from commercially available chiral amino acids. The multifunctional role of MIQOXs was demonstrated by Pd-catalyzed highly enantioselective addition of arylboronic acids to nitrostyrenes, and by the discovery of novel antifungal candidates.
Synthesis of palladium nanoparticles using triazolium based ionic liquids: A reusable catalyst for addition of arylboronic acids to nitrostyrenes
Sundararaju, Kavya,Veeraragavan, VijayaKumar,Chidambaram, Ramesh Kumar
supporting information, p. 3000 - 3014 (2018/12/04)
Formation of stable and small-sized palladium nanoparticles of diameter 9.4 nm was accomplished by a simple heating of Pd(OAc)2 in 1-octyl-1,2,4-triazolium trifluoroacetate ionic liquid under standard atmospheric hydrogen pressure. Palladium na
Stable and Reusable Palladium Nanoparticles-Catalyzed Conjugate Addition of Aryl Iodides to Enones: Route to Reductive Heck Products
Parveen, Naziya,Saha, Rajib,Sekar, Govindasamy
, p. 3741 - 3751 (2017/11/15)
An efficient, binaphthyl-backbone-stabilized palladium nanoparticles (Pd-BNP) catalyst for the 1,4-addition of aryl halides to enones has been developed. The scope of the reaction has been studied with various substituted and sterically hindered aryl hali
A nordehydroabietyl amide-containing chiral diene for rhodium-catalysed asymmetric arylation to nitroolefins
Li, Ruikun,Wen, Zhongqing,Wu, Na
supporting information, p. 11080 - 11084 (2016/12/07)
A highly enantioselective rhodium catalysed asymmetric arylation (RCAA) of nitroolefins with arylboronic acids is presented using a newly developed, C1-symmetric, non-covalent interacted, phellandrene derived, nordehydroabietyl amide-containing chiral diene under mild conditions. Stereoelectronic effects were studied, suggesting an activation of the bound substrate through the secondary amide as a hydrogen-bond donor.
Palladium-catalyzed asymmetric addition of arylboronic acids to nitrostyrenes
He, Qun,Xie, Fang,Fu, Guanghong,Quan, Mao,Shen, Chaoren,Yang, Guoqiang,Gridnev, Ilya D.,Zhang, Wanbin
supporting information, p. 2250 - 2253 (2015/05/13)
A palladium-catalyzed asymmetric addition of arylboronic acids to nitrostyrene is reported. The catalytic system employing iPr-IsoQuinox as a chiral ligand in MeOH solvent under an air atmosphere provides the chiral diarylsubstituted products in high yields with good enantioselectivities. A variety of functionalized nitrostyrenes can be used, and the method tolerates some variation in arylboronic acid scope. The stereochemical outcome can be explained using a stereochemical model.
Nitroalkenes as surrogates for cyanomethylium species in a one-pot synthesis of non-symmetric diarylacetonitriles
Aksenov, Alexander V.,Aksenov, Nicolai A.,Dzhandigova, Zarema V.,Aksenov, Dmitrii A.,Rubin, Michael
, p. 106492 - 106497 (2016/01/15)
Nitroalkenes were used as synthetic equivalents of the cyanomethylium cation in a modular, one-pot synthesis of 2-(3-indolyl)acetonitriles and 2,2-diarylacetonitriles involving electrophilic functionalization of aromatic and heteroaromatic C-H bond.
Pd-NHC catalyzed conjugate addition versus the mizoroki-heck reaction
Gottumukkala, Aditya L.,Devries, Johannes G.,Minnaard, Adriaan J.
supporting information; experimental part, p. 3091 - 3095 (2011/04/22)
Ace of base: A catalytic system is presented that, solely by choice of the base, selectively switches between conjugate addition and the Mizoroki-Heck reaction of aryl halides with Michael acceptors (see scheme; R, R′=alkyl, aryl). For conjugate addition reactions, this avoids the preparation and use of organometallics.
THIAZOLYL COMPOUNDS USEFUL AS KINASE INHIBITORS
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Page/Page column 31, (2010/03/31)
The invention provides compounds of formula I [INSERT CHEMICAL STRUCTURE HERE] (I) and pharmaceutically acceptable salts thereof. The formula I thiazolyl compounds inhibit tyrosine kinase activity thereby making them useful as anticancer agents and for the treatment of Alzheimer's Disease.
