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5144-52-5

5144-52-5

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5144-52-5 Usage

Chemical Properties

White or almost white, crystalline powder.

Indications

Naphazoline hydrochloride and naphazoline nitrate are white or almost white crystalline powders soluble 1 in 6 and 1 in 36 water, respectively. These are potent sympathomimetic vasoconstrictors with a direct alpha-adrenergic receptor stimulatory action, and may be used as topical decongestants in 0.05% or 0.1% eyedrops. Frequent application of these solutions will produce a reactive hyperaemia. Instillation should not be repeated in less than 4-6 hours to avoid this rebound congestion. Naphazoline eyedrops cause slight mydriasis and are contra-indicated in patients with actual or suspected closed-angle glaucoma. Although not administered systemically, topical application of naphazoline has resulted in systemic absorption, and it is readily absorbed from the gastro-intestinal tract (Martindale, 1977).

Check Digit Verification of cas no

The CAS Registry Mumber 5144-52-5 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,1,4 and 4 respectively; the second part has 2 digits, 5 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 5144-52:
(6*5)+(5*1)+(4*4)+(3*4)+(2*5)+(1*2)=75
75 % 10 = 5
So 5144-52-5 is a valid CAS Registry Number.
InChI:InChI=1/C14H14N2.HNO3/c1-2-7-13-11(4-1)5-3-6-12(13)10-14-15-8-9-16-14;2-1(3)4/h1-7H,8-10H2,(H,15,16);(H,2,3,4)/p+1

5144-52-5 Well-known Company Product Price

  • Brand
  • (Code)Product description
  • CAS number
  • Packaging
  • Price
  • Detail

  • Alfa Aesar

  • (L12617)  2-(1-Naphthylmethyl)-2-imidazoline nitrate, 99%   

  • 5144-52-5

  • 25g

  • 400.0CNY

  • Detail

  • Alfa Aesar

  • (L12617)  2-(1-Naphthylmethyl)-2-imidazoline nitrate, 99%   

  • 5144-52-5

  • 100g

  • 1244.0CNY

  • Detail

  • Aldrich

  • (70170)  Naphazolinenitrate  ≥99.0% (NT)

  • 5144-52-5

  • 70170-25G

  • 520.65CNY

  • Detail

  • Sigma-Aldrich

  • (N0100000)  Naphazolinenitrate  European Pharmacopoeia (EP) Reference Standard

  • 5144-52-5

  • N0100000

  • 1,880.19CNY

  • Detail

5144-52-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 14, 2017

Revision Date: Aug 14, 2017

1.Identification

1.1 GHS Product identifier

Product name Naphazoline nitrate

1.2 Other means of identification

Product number -
Other names privinenitrate

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:5144-52-5 SDS

5144-52-5Synthetic route

Naphazoline nitrate
5144-52-5

Naphazoline nitrate

bis-(2,4-dihydroxythiobenzoyl)sulfinyl
344567-18-6

bis-(2,4-dihydroxythiobenzoyl)sulfinyl

2-(1-naphthylmethyl)-1-(2,4-dihydroxythiobenzoyl)-2-imidazoline

2-(1-naphthylmethyl)-1-(2,4-dihydroxythiobenzoyl)-2-imidazoline

Conditions
ConditionsYield
With pyridine In methanol for 10h; Heating;

5144-52-5Upstream product

5144-52-5Downstream Products

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