17β-Estradiol-17β-carbamat, also known as Estramustine, is a chemical compound with the molecular formula C28H37Cl2NO4. It is a derivative of the naturally occurring hormone 17β-estradiol, which is a form of estrogen. 17β-Estradiol-17β-carbamat is characterized by the presence of two chloroethyl groups attached to the nitrogen atoms of a carbamate group, which is in turn linked to the 17β position of the estradiol molecule. Estramustine is primarily used as an antineoplastic agent, specifically in the treatment of prostate cancer and certain types of breast cancer. It works by inhibiting microtubule formation, which disrupts cell division, and by binding to the estrogen receptor, which can affect the growth of hormone-sensitive tumors. The compound's dual mechanism of action makes it a unique therapeutic option in oncology.

5146-45-2

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Basic information
1. Product Name: 17β-Estradiol-17β-carbamat
2. Synonyms: 17β-Estradiol-17β-carbamat
3. CAS NO:5146-45-2
4. Molecular Formula:
5. Molecular Weight: 440.41
6. EINECS: N/A
7. Product Categories: N/A
Chemical Properties
1. Melting Point: N/A
2. Boiling Point: N/A
3. Flash Point: N/A
4. Appearance: N/A
5. Density: N/A
6. Refractive Index: N/A
7. Storage Temp.: N/A
8. Solubility: N/A
9. CAS DataBase Reference: 17β-Estradiol-17β-carbamat(CAS DataBase Reference)
10. NIST Chemistry Reference: 17β-Estradiol-17β-carbamat(5146-45-2)
11. EPA Substance Registry System: 17β-Estradiol-17β-carbamat(5146-45-2)
Safety Data
1. Hazard Codes: N/A
2. Statements: N/A
3. Safety Statements: N/A
4. WGK Germany:
5. RTECS:
6. HazardClass: N/A
7. PackingGroup: N/A
8. Hazardous Substances Data: 5146-45-2(Hazardous Substances Data)

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Check Digit Verification of cas no

The CAS Registry Mumber 5146-45-2 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,1,4 and 6 respectively; the second part has 2 digits, 4 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 5146-45:
(6*5)+(5*1)+(4*4)+(3*6)+(2*4)+(1*5)=82
82 % 10 = 2
So 5146-45-2 is a valid CAS Registry Number.

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