51463-49-1Relevant academic research and scientific papers
Substituent controlled reactivity switch: Selective synthesis of α-diazoalkylphosphonates or vinylphosphonates via nucleophilic substitution of alkyl bromides with Bestmann-Ohira reagent
Pramanik, Mukund M. D.,Chaturvedi, Atul Kumar,Rastogi, Namrata
, p. 12896 - 12898 (2014)
We report a substituent controlled nucleophilic displacement of alkyl bromides with Bestmann-Ohira reagent yielding either dimethyl diazoalkylphosphonates or (E)-vinylphosphonates. The dimethyl diazoalkylphosphonates could be readily converted into corresponding (E)-vinylphosphonates in the presence of Cu following nitrogen elimination in quantitative yields. This journal is
