515173-89-4

Upstream product

• 515173-86-1 (1'S,4S)-4-(2'-ethoxycarbonylmethyl-1'-phenyl-ethyl)-2,2-dimethyl-oxazolidine-3-carboxylic acid tert-butyl ester 
• 134525-18-1 (2E',4S)-4-(2'-ethoxycarbonyl-vinyl)-2,2-dimethyl-oxazolidine-3-carboxylic acid tert-butyl ester 
• 95715-87-0 (R)-3-tert-butoxycarbonyl-4-formyl-2,2-dimethyloxazolidine 

Downstream Products

• 515173-95-2 (2S,3S)-2-tert-butoxycarbonylamino-5-methanesulfonyloxy-3-phenyl-pentanoic acid methyl ester 
• 515173-98-5 (2S,3S)-3-phenyl-pyrrolidine-1,2-dicarboxylic acid 1-tert-butyl ester 2-methyl ester 
• 862473-13-0 pentafluorophenyl (2S,3S,1'S)-5-[benzyloxycarbonyl-(1'-methoxycarbonyl-3'-methylbutyl)amino]-2-tert-butoxycarbonylamino-3-phenyl-pentanoate 
• 862473-11-8 (2S,3S,1'S)-5-[benzyloxycarbonyl-(1'-methoxycarbonyl-3'-methylbutyl)amino]-2-tert-butoxycarbonylamino-3-phenyl-pentanoic acid 
• 862473-10-7 (4S,1'S,1''S)-4-{3'-[benzyloxycarbonyl-(1''-methoxycarbonyl-3''-methylbutyl)amino]-1'-phenylpropyl}-2,2-dimethyloxazolidine-3-carboxylic acid tert-butyl ester 
• 862473-09-4 (4S,1'S,1''S)-4-[3'-(1''-methoxycarbonyl-3''-methylbutylamino)-1'-phenylpropyl]-2,2-dimethyloxazolidine-3-carboxylic acid tert-butyl ester 
• 515173-92-9 (1'S,4S)-4-(3'-methanesulfonyloxy-1'-phenylpropyl)-2,2-dimethyl-oxazolidine-3-carboxylic acid tert-butyl ester 
• 862473-07-2 (4S,1'S)-2,2-dimethyl-4-(3'-oxo-1'-phenylpropyl)oxazolidine-3-carboxylic acid tert-butyl ester 

Relevant academic research and scientific papers

Synthesis of 4-substituted-3-aminopiperidin-2-ones: Application to the synthesis of a conformationally constrained tetrapeptide N-acetyl-Ser-Asp-Lys- Pro

A new and practical synthetic strategy is developed for the synthesis of six-membered lactam-bridged dipeptides, 4-substituted-3-aminopiperidin-2-ones, featuring two key steps: (a) a diastereoselective addition of cuprate to (E)-α,β-unsaturated ester (3)

An efficient method for the stereoselective synthesis of cis-3-substituted prolines: Conformationally constrained α-amino acids

An efficient synthesis of enantiomerically pure cis-3-substituted prolines is reported. Key steps involve the stereoselective organocuprate addition to the (E)-α,β-unsaturated ester 1, obtained from the Garner's aldehyde, and expedient oxidation-cyclizati