515173-92-9

Upstream product

• 124-63-0 methanesulfonyl chloride 
• 515173-89-4 (1'S,4S)-4-(3'-hydroxy-1'-phenyl-propyl)-2,2-dimethyl-oxazolidine-3-carboxylic acid tert-butyl ester 
• 515173-86-1 (1'S,4S)-4-(2'-ethoxycarbonylmethyl-1'-phenyl-ethyl)-2,2-dimethyl-oxazolidine-3-carboxylic acid tert-butyl ester 
• 134525-18-1 (2E',4S)-4-(2'-ethoxycarbonyl-vinyl)-2,2-dimethyl-oxazolidine-3-carboxylic acid tert-butyl ester 
• 95715-87-0 (R)-3-tert-butoxycarbonyl-4-formyl-2,2-dimethyloxazolidine 

Downstream Products

• 515173-95-2 (2S,3S)-2-tert-butoxycarbonylamino-5-methanesulfonyloxy-3-phenyl-pentanoic acid methyl ester 
• 515173-98-5 (2S,3S)-3-phenyl-pyrrolidine-1,2-dicarboxylic acid 1-tert-butyl ester 2-methyl ester 

Relevant academic research and scientific papers

An efficient method for the stereoselective synthesis of cis-3-substituted prolines: Conformationally constrained α-amino acids

An efficient synthesis of enantiomerically pure cis-3-substituted prolines is reported. Key steps involve the stereoselective organocuprate addition to the (E)-α,β-unsaturated ester 1, obtained from the Garner's aldehyde, and expedient oxidation-cyclizati