5153-63-9

Usage

Uses

Used in Organic Synthesis:
Pyridinium acetate is used as a reagent for various organic synthesis processes. Its role in these reactions is to facilitate the formation of desired products by acting as a catalyst or participating in the reaction mechanism.
Used in Laboratory Research:
Due to its solubility in water, pyridinium acetate is used in laboratory research as a convenient compound for conducting experiments. Its ease of handling and reactivity make it a valuable tool for scientists working in the field of organic chemistry.
Used in Chemical Education:
Pyridinium acetate can be used as an educational tool in teaching organic chemistry, particularly in illustrating the properties and reactions of acetic acid derivatives and pyridine-based compounds. Its reactivity and solubility provide a practical example for students to understand the principles of organic synthesis and reactivity.
Used in Industrial Applications:
Pyridinium acetate may also find use in industrial applications where its reactivity and properties are required for the production of specific chemical products. Its versatility as a reagent in organic synthesis can be harnessed in the development of new compounds and materials.

InChI:InChI=1/C5H5N.C2H4O2/c1-2-4-6-5-3-1;1-2(3)4/h1-5H;1H3,(H,3,4)

Upstream product

• 110-86-1 pyridine 
• 64-19-7 acetic acid 
• 694-59-7 pyridine N-oxide 

Downstream Products

• 100-32-3 di(p-nitrophenyl) disulfide 
• 23848-94-4 1t.4-diphenyl-pentadien-(1.3ξ)-oic acid-(5) 

Relevant academic research and scientific papers

Effect of pyridinium based ionic liquid on the sensing property of Ni0 nanoparticle for the colorimetric detection of hydrogen peroxide

In this work, we presented a new colorimetric technique for the easy and quick detection of hydrogen peroxide. Two types of ionic liquids namely imidazolium and pyridinium containing cations with an acetate anion were evaluated in this study. Ni nanoparticle is synthesized using the wet chemical method, which is further characterized using various analytical techniques. Ni nanoparticles coated with pyridinium based ionic liquid showed robust peroxidase-like activity, which resulted in better dispersion of nickel nanoparticle and is able to quickly catalyze the oxidation reaction of substrate 3,3,5,5-tetramethylbenzidine (TMB) in the presence of hydrogen peroxide (H2O2), leading to the generation of a blue-colored solution. On the basis of color development, colorimetric sensing of [Pyr]Ac- Ni0 was achieved with a detection limit (LOD) of 120 μM/L within a linear range of 400–4000 μM. The proposed method is significantly selective for [Pyr]Ac- Ni0and can be conveniently and affordably applied to the detection of hydrogen peroxide without any complicated instrumentation.

Bringing a Molecular plus One: Synergistic Binding Creates Guest-Mediated Three-Component Complexes

Cethyl-2-methylresorcinarene (A), pyridine (B), and a set of 10 carboxylic acids (Cn) associate to form A·B·Cn ternary assemblies with 1:1:1 stoichiometry, representing a useful class of ternary systems where the guest mediates complex formation between the host and a third component. Although individually weak in solution, the combined strength of the multiple noncovalent interactions organizes the complexes even in a highly hydrogen-bond competing methanol solution, as explored by both experimental and computational methods. The interactions between A·B and Cn are dependent on the pKa values of carboxylic acids. The weak interactions between A and C further reinforce the interactions between A and B, demonstrating positive cooperativity. Our results reveal that the two-component system such as that formed by A and B can form the basis for the development of specific sensors for the molecular recognition of carboxylic acids.

PROCESS FOR THE PREPARATION OF ILOPROST

The present invention relates to a process for the preparation of iloprost of formula I through new intermediates, isolation of iloprost of formula I in solid form, as well as preparation of the 16(S)-iloprost and 16(R)-iloprost isomers of formulae (S)-I and (R)-I and isolation of iloprost of formula I and 16(S)-iloprost of formula (S)-I in solid, crystalline form.

Preparation method of key midbody allene sulfoxide matter of dexamethasone

The invention discloses a preparation method of key midbody allene sulfoxide matter of dexamethasone. The preparation method includes steps of adding an organic solvent (I) containing weak acid and weak base salt to a compound shown in Formula A; then adding to an organic solvent (II) containing chorine fenbendazole and reacting; after reaction, collecting a compound shown in Formula B from a reaction product. The method has the beneficial effects that the product does not use cyanide and heavy metals, and is good for large-scale industrial production; the yield is over 124%, which is greatly higher than that of the prior art; the production cost is reduced, and the technical innovation of the preparation technique of dexamethasone and other steroids containing C17 side chain is promoted; meanwhile, the method also provides a thinking for the preparation of the steroids with the side chain. The reaction general formula is shown as below: FORMULA.

Tunable protic ionic liquids as solvent-catalysts for improved synthesis of multiply substituted 1,2,4-triazoles from oxadiazoles and organoamines

More than green alternatives to traditional volatile molecular organic solvents, protic ionic liquids as dual solvent-catalysts have been successfully used to promote reactions of organoamines with oxadiazoles to afford sterically hindered 1,2,4-triazoles. Among the tested protic ionic liquids, pyridinium trifluoroacetate and acetate showed the highest efficiency for the reactions of arylamines and alkylamines, respectively, indicating that tunable catalysis could be readily effected with protic ionic liquid solvent-catalysts by simply tuning their cation and anion counterparts. A general and efficient approach has been developed for synthesis of multiply substituted 1,2,4-triazoles based on the tunable protic ionic liquid solvent-catalyst systems.

Substituted biphenyls

Substituted biphenyls having glucagon receptor antagonistic activity. Claimed compounds have the formula wherein R1aand R1bindependently represent (C1-C6) alkyl; R2represents (C1-C10) alkyl or substituted (C1-C10) alkyl wherein the substituents are independently from 1 to 3 of —SR7; R7represents phenyl, or substituted phenyl wherein the substituents are independently 1-5 of halogen, trifluoromethyl, (C1-C6) alkyl, (C1-C6) alkoxy, nitro, cyano, or hydroxyl; R3represents substituted (C1-C6) alkyl wherein the substituents are 1-2 hydroxyl groups; G represents a substituent selected from the group consisting of halogen, (C1-C6) alkyl, and OR4wherein R4is H or (C1-C6) alkyl; and y is 0 or an integer of 1-3. Pharmaceutical compositions containing such compounds and methods of treatment of glucagon-mediated conditions by administering such compounds are also claimed.

Method for synthesizing esters

A method for preparing an ester having the structure STR1 in which A is an acid residue; R, same or different is H, lower alkyl, aryl, or in which both R together form a ring structure and R' is H, lower alkyl or aryl. The method comprises combining a first compound having the structure STR2 and a second compound which is an acyl halide corresponding to A, said combining being performed in the presence of an organic acid.

Hydrogen-Bonded Species of Pyridinium Halogenoacetetes. 2. Thermometric Behavior in Aprotic Solvents

The enthalpies of reaction of a series of substituted pyridines and of triethylamine, quinoline, and isoquinoline (for the sake of comparison) with trifluoroacetic acid (TFA) in chloroform were measured at 25 deg C at final solution concentrations ranging from 1E-2 to 5E-2 M.The enthalpies of reaction of 2,4,6-trimethylpyridine, pyridine, and 4-cyanopyridine with trichloroacetic acid (TCA), dichloroacetic acid (DCA), monochloroacetic acid (MCA), and acetic acid (AcOH) in chloroform were also measured at 25 deg C.The concentration dependence of enthalpies of reaction was examined by measuring them for 2,4,6-trimethylpyridine-TFA, pyridine-TFA, and 4-cyanopyridine-TFA in chloroform over the entire possible solution concentration range at 25 deg C.In order to study the energetic behavior of H-bonded species of the ptridine-TFA system in media of different dielectric constants, the enthalpy measurements were made in p-dioxane, o-xylene, and carbon tetrachloride.The thermometric results have been discussed in terms of interactions present in the H-bonded species of these systems in nonaqueous solutions.