51531-18-1

Upstream product

• 107448-94-2 O-biphenyl-3-yl-hydroxylamine 
• 1079392-34-9 C₂₀H₁₃NO₃ 
• 5122-95-2 3-Biphenylboronic acid 
• 611-73-4 Benzoylformic acid 

Downstream Products

• 1334247-33-4 (S)-4-(amino(phenyl)methyl)-[1,1'-biphenyl]-3-ol 
• 1334335-01-1 4-(imino(phenyl)methyl)-[1,1'-biphenyl]-3-ol 

Relevant academic research and scientific papers

RhIII-Catalyzed Decarboxylative o-Acylation of Arenes Bearing an Oxidizing Directing Group

Here in we report, rhodium(III)-catalyzed decarboxylative acylation of arenes using α-oxocarboxylic acids as acyl surrogate. In this strategy, O–NHAc group act as an autocleavable oxidizing directing group (ODGauto), thus giving rise to ortho-acylated phenols in moderate to good yields. Mechanistic studies provided strong support for a kinetically relevant C–H bond activation. According to the best of our knowledge, this is the first report of Rhodium catalyzed decarboxylative acylation.