51571-49-4Relevant academic research and scientific papers
Synthesis of Novel Heterocycles Derived from 4-Arylmethylene-2-phenyl-1,3-oxazole-5(4H)-ones
Youssef, Ahmed S. A.,Kandeel, Kamal A.,Abou-Elmagd, Wael S.I.,Haneen, David S. A.
, p. 809 - 816 (2016)
The acid hydrazide derivatives 2 were converted into pyrazolone, triazinone, and schiff bases. However, the reaction of Schiff base 12 with malononitrile or thioglycolic acid gives the pyrazolotriazinone or thiazolidinone derivative, respectively. The str
Thiosemicarbazide Derivatives as Building Block in Synthesis of Target Heterocyclic Compounds with Their Antimicrobial Assessment
Abou Elmagd, Wael S. I.,Hemdan, Magdy M.,Samy, Sandy S.,Youssef, Ahmed S. A.
, p. 1391 - 1395 (2017/03/27)
1-(2-Benzamido-3-(1,3-diphenyl-1H-pyrazol-4-yl)acryloyl)-4-phenylthiosemicarbazide is used as precursor for synthesis of imidazole, 1,3,4-oxadiazole, 1,3,4-thiadiazole, 1,3-oxazine, and 1,2,4-triazine ring systems. The antimicrobial activity of some of th
Action of Some Nitrogen and Carbon Nucleophils on 4-Arylidene-1,3-oxazolones
Youssef, Ahmed S. A.,Kandeel, Kamal A.,Abou-Elmagd, Wael S. I.,Haneen, David S. A.
, p. 175 - 182 (2015/03/04)
(Chemical Equation Presented) 1,3-Oxazolones 1 and 2 were reacted with hydrazine hydrate to afford the corresponding hydrazides 3 and 4. Treatment of the hydrazides withacetylacetone, acetonylacetone, ethyl acetoacetate and diethyl malonateyielded different heterocycles. However, oxazolones 1 and 2 reacted with methyl p-aminobenzoate to afford the imidazolones 5a,b which were converted into the hydrazide 3a or the triazinone derivative 6 upon treating with hydrazine hydrate. The structures of the newly synthesized compounds were established using IR, 1H-NMR, EIMS, and elemental analyses.
