51578-64-4Relevant academic research and scientific papers
Photocatalytic Barbier reaction-visible-light induced allylation and benzylation of aldehydes and ketones
Berger, Anna Lucia,Donabauer, Karsten,K?nig, Burkhard
, p. 7230 - 7235 (2018/10/02)
We report a photocatalytic version of the Barbier type reaction using readily available allyl or benzyl bromides and aromatic aldehydes or ketones as starting materials to generate allylic or benzylic alcohols. The reaction proceeds at room temperature under visible light irradiation with the organic dye 3,7-di(4-biphenyl)1-naphthalene-10-phenoxazine as a photocatalyst and DIPEA as sacrificial electron donor. The proposed cross-coupling mechanism of a ketyl- and an allyl or benzyl radical is supported by spectroscopic investigations and cyclic voltammetry measurements.
McMurry coupling of aryl aldehydes and imino pinacol coupling mediated by Ti(O-i-Pr)4/Me3SiCl/Mg reagent
Okamoto, Sentaro,He, Jing-Qian,Ohno, Chihaya,Oh-iwa, Yuhji,Kawaguchi, Yuhki
experimental part, p. 387 - 390 (2010/03/03)
Ti(O-i-Pr)4/Me3SiCl/Mg reagent mediated McMurry coupling of aryl aldehydes to biaryl olefins at near room temperature. This low valent titanium (LVT) reagent also mediated the coupling of aldimines to 1,2-diamines (imino pinacol coupling).
A convenient synthesis of unsymmetrical pinacols by coupling of structurally similar aromatic aldehydes mediated by low-valent titanium
Duan, Xin-Fang,Feng, Jian-Xia,Zi, Guo-Fu,Zhang, Zhan-Bin
experimental part, p. 277 - 282 (2009/06/24)
The one-pot, selective cross pinacol-type couplings between two structurally similar aromatic aldehydes promoted by low-valent titanium generated unsymmetrical pinacols in moderate to good isolated yields in an erythrolthreo ratio of up to 91:9. This synt
