51579-81-8Relevant academic research and scientific papers
Antiinflammatory agents. 3. Synthesis and pharmacological evaluation of 2-amino-3-benzoylphenylacetic acid and analogues
Walsh,Moran,Shamblee,Uwaydah,Welstead Jr.,Sancilio,Dannenburg
, p. 1379 - 1388 (2007/10/02)
A series of substituted derivatives of 2-amino-3-benzoylphenylacetic acid (amfenac) has been synthesized and evaluated for antiinflammatory, analgesic, and cyclooxygenase inhibiting activity. Several derivatives including 4'-chloro, 4'-bromo and 5-chloro, 4'-bromo were more potent than indomethacin in these assays.
Anti-inflammatory methods using 2-amino-3-(5- and 6-)benzoylphenylacetic acids, esters and metal salts thereof and the compounds
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, (2008/06/13)
Novel 2-amino-3-(5- and 6-)benzoylphenylacetic acids, esters and metal salts of the formula: STR1 wherein R is hydrogen or lower alkyl, R1 is hydrogen, lower-alkyl, sodium or potassium, R2 is hydrogen, halogen or lower alkoxy, X is h
