51626-33-6

Usage

Uses

Used in Pharmaceutical Research:
5-CHLORO-3-METHYL-1-PHENYL-1H-PYRAZOLE-4-CARBONITRILE is used as a key intermediate in the synthesis of pharmaceutical drugs for its potential biological activities. It contributes to the development of new therapeutic agents targeting a range of medical conditions.
Used in Agrochemicals:
In the agrochemical industry, 5-CHLORO-3-METHYL-1-PHENYL-1H-PYRAZOLE-4-CARBONITRILE is used as a building block in the creation of various agrochemicals. Its incorporation aids in the development of effective compounds for crop protection and enhancement of agricultural productivity.
Used in Organic Synthesis:
5-CHLORO-3-METHYL-1-PHENYL-1H-PYRAZOLE-4-CARBONITRILE serves as a valuable component in organic synthesis, where it is employed as a reactant or a precursor to construct more complex organic molecules with diverse applications in various industries.

InChI:InChI=1/C11H8ClN3/c1-8-10(7-13)11(12)15(14-8)9-5-3-2-4-6-9/h2-6H,1H3

Upstream product

• 89-25-8 edaravone 
• 947-95-5 5-chloro-4-formyl-3-methyl-1-phenyl-1H-pyrazole 
• 51626-34-7 5-chloro-3-methyl-1-phenyl-1H-pyrazole-4-carbaldehyde oxime 

Relevant academic research and scientific papers

A convenient synthesis, reactions and biological studies of some novel selenolo[2,3-c]pyrazole compounds as antimicrobial and anti-inflammatory agents

5-Chloro-3-methyl-1-phenylpyrazole-4-carbonitrile 3 was reacted with selenium in the presence of sodium borohydride and chloroacetamide to afford selanyl acetamide 5, which underwent Thorpe-Ziegler cyclization upon heating with sodium ethoxide to give the

A convenient synthesis and biological activity of novel thieno[2,3-c]pyrazole compounds as antimicrobial and anti-inflammatory agents

A new method for synthesizing 4-amino-3-methyl-1-phenyl-1H-5-substituted thieno[2,3-c]pyrazole was reported. The substituted groups at position 5 include carbonitrile, carboxamide, N-phenyl carboxamide, and benzoyl groups. The newly synthesized compounds

Thieno[2,3-c]pyrazoles and related heterocycles

5-Chloro-3-methyl-1-phenyl-1H-pyrazole-4-carboxaldehyde (1) was converted, via the oxime 2, into the chloronitrile 3. Treatment of compound 3 with methyl thioglycolate gave the novel methyl 4-amino-3-methyl-1-phenyl-1H-thieno [2,3-c]pyrazole-5-carboxylate

GROUP DIPOLE MOMENTS OF SUBSTITUENTS AT POSITIONS 4 AND 5 OF NITROGEN-CONTAINING FIVE-MEMBERED HETEROCYCLES

The dipole moments of the 5-chloro-4-cyano derivatives of oxazole, thiazole, imidazole, and pyrazole were determined.The group dipole moments of substituents at positions 2 and 3 of furan, thiophene, and pyrrole can be used for vector calculation of the dipole moments of various 4- and 5-substituted azoles.