54382-74-0 Usage
Uses
Used in Pharmaceutical Industry:
16-PHENOXY TETRANOR PROSTAGLANDIN E2 is used as an intermediate compound for the synthesis of various prostaglandin analogs. Its role in the pharmaceutical industry is crucial for developing medications that target specific prostaglandin receptors, which can have applications in treating a range of conditions, including cardiovascular diseases, gastrointestinal disorders, and reproductive system issues.
Used in Research and Development:
In the field of research and development, 16-PHENOXY TETRANOR PROSTAGLANDIN E2 serves as a valuable compound for studying the effects and mechanisms of prostaglandins. This can lead to a better understanding of their role in various physiological processes and the development of new therapeutic strategies targeting prostaglandin pathways.
Used in Diagnostic Applications:
16-PHENOXY TETRANOR PROSTAGLANDIN E2 can be utilized in diagnostic applications to detect and monitor the levels of this metabolite in human plasma. This can be particularly useful in assessing the efficacy of sulprostone administration and understanding its metabolic pathways in the body.
Check Digit Verification of cas no
The CAS Registry Mumber 54382-74-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,4,3,8 and 2 respectively; the second part has 2 digits, 7 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 54382-74:
(7*5)+(6*4)+(5*3)+(4*8)+(3*2)+(2*7)+(1*4)=130
130 % 10 = 0
So 54382-74-0 is a valid CAS Registry Number.
54382-74-0Relevant academic research and scientific papers
N-(Methanesulfonyl)-16-phenoxyprostaglandincarboxamides: Tissue-Selective, Uterine Stimulants
Schaaf, Thomas K.,Bindra, Jasjit S.,Eggler, James F.,Plattner, Jacob J.,Nelson, A. James,et al.
, p. 1353 - 1359 (2007/10/02)
In an effort to develop tissue-selective prostaglandin analogues resistant to the metabolic inactivating pathways of the natural materials, hybrid compounds modified both at C-1 with a sulfonimide moiety and in the n-amylcarbinol side chain with substituted phenoxy groups were synthesized and evaluated in a variety of in vitro and in vivo models.Several of these analogues exhibited potent, tissue-selective, uterine stimulant activity, a finding subsequently confirmed in clinical studies with one member of this series, N-(methanesulfonyl)-16-phenoxy-ω-tetranor-PGE2-carboxamide (CP-34089/ZK-57671, sulprostone).
