51675-55-9Relevant academic research and scientific papers
Zinc-catalyzed transformation of diarylphosphoryl azides to diarylphosphate esters and amides
Ying, Jun,Gao, Qian,Wu, Xiao-Feng
, p. 1540 - 1543 (2020/04/15)
We have developed a facile and efficient procedure for the synthesis of diarylphosphate esters and amides. Using Zn(acac)2 as the catalyst, the reaction of diarylphosphoryl azides with aliphatic alcohols and phenols through an unusual P?N bond cleavage provided a number of diarylphosphate esters in good yields (22 examples, up to 94%). Additionally, various diarylphosphate amides were obtained from the corresponding amines in excellent yields as well (8 examples, up to 96%).
Mode of alkylation of alcohols with O-cyclopropylmethyl trichloroacetimidate and O-cyclobutyl trichloroacetimidate
Ali, Ibrahim A.I.,Zhu, Xiangming,El Ashry, El Sayed H.,Schmidta, Richard R.
experimental part, p. 35 - 44 (2012/03/09)
Acid promoted alkylation of hydroxy group containing acceptors 3-14 with O-cyclopropylmethyl and O-cyclobutyl trichloroacetimidates 1 and 2, respectively, afforded ethers with cyclopropylmethyl, cyclobutyl, and homoallyl residues as a result of the rearrangement of the cation intermediates. The dependence of product formation on acceptor structure is discussed. ARKAT-USA, Inc.
3-Phosphono-2-(N-cyanoimino)thiazolidine derivatives, new phosphorylating agents for alcohols
Maezaki, Naoyoshi,Furusawa, Akemi,Hirose, Yuki,Uchida, Shuji,Tanaka, Tetsuaki
, p. 3493 - 3498 (2007/10/03)
We have developed new phosphorylating agents, 3-phosphono-2-(N-cyanoimino)-thiazolidine derivatives (3-phosphono-NCTs), which were readily synthesized by phosphorylation of NCT, and transformed primary and secondary alcohols into phosphates in good yield. The transfer of three kinds of dialkylphosphono groups [(PhO)2P(O)-, (EtO)2P(O)-, (Cl3CCH2O)2P(O)-] proceeded in excellent yields. Selective phosphorylation of various alcohols was also accomplished.
IODINE INDUCED CYCLIZATION OF ORGANOPHOSPHORUS COMPOUNDS
Ye, Mao-Chun,Li, Li-Pou,Zhao, Yu-Fen,Zhai, Chun
, p. 79 - 88 (2007/10/02)
The iodine induced cyclization reaction of unsaturated phosphates, phosphonates and phosphoamidates was studied.It was found that the nucleophilicity of the phosphoryl oxygen was affected by the substituent on phosphorus and the reactivity of the unsaturated center was perturbed by the neighboring atoms or groups.The P-31 NMR spectra and other spectroscopy techniques proved, the existence of the diiodo-compounds and the cyclic phosphonium ions as the reaction intermediates.Key words: Electrophile induced cyclization; phosphoryl oxygen as nucleophilic center; structural effects on cyclization reaction.
