51679-32-4

Upstream product

• 107454-83-1 1-(nitromethyl)-1,2-epoxycyclohexane 
• 930-69-8 sodium thiophenolate 
• 1125-99-1 1-(1-Cyclohexen-1-yl)pyrrolidine 
• 1193-82-4 racemic methyl phenyl sulfoxide 
• 6651-36-1 1-(Trimethylsilyloxy)cyclohexene 
• 13865-50-4 methoxymethyl phenyl sulfide 
• 670-80-4 4-cyclohexen-1-ylmorpholine 
• 13815-46-8 N,N-dimethylcyclohex-1-enylamine 
• 120-92-3 cyclopentanone 
• 1655-07-8 ethyl 2-oxocyclohexane carboxylate 
• 70301-49-4 2,2-dimethoxycyclohexanecarboxylic acid ethyl ester 
• 7500-52-9 (2-oxocyclohexyl)methyl acetate 
• 150970-28-8 (2,2-dimethoxycyclohexyl)methanol 
• 5330-61-0 1-nitromethyl-cyclohexene 

Downstream Products

• 51679-33-5 2-Phenylsulfanylmethyl-cyclopentanone 
• 1338468-12-4 C₁₃H₁₆O₂S 

Relevant academic research and scientific papers

The enantioselective synthesis of tetracyclic methyllycaconitine analogues

A new enantioselective synthesis of ABEF ring analogues of methyllycaconitine has been developed using a chiral cobalt(III) salen-catalyzed Diels-Alder reaction to form the B ring. Subsequent elaboration to form the A, E and F rings was achieved by sequential Dieckmann, Mannich and Wacker-type cyclizations to afford tetracyclic analogues in 97.5% ee.

Lewis acid mediated selective chalcogenalkylation of silyl enol ethers with [O,S]-acetals

Silyl enol ethers of ketones were selectively alkylated with [O,S]- acetals mediated by Lewis acid in a Mukaiyama type Aldol reaction. The products were β-alkoxy- and/or β-sulfanyl carbonyl compounds depending on the catalyst employed.

α-Sulfenylalkylation of carbonyl compounds at the α-position via magnesium amide-induced enamine sulfenylalkylation with sulfoxides

The reactions of enamines with sulfoxides bearing α-hydrogens in the presence of a magnesium amide, generated in situ from the reaction of ethylmagnesium bromide with diisopropylamine, afforded the corresponding α-sulfenylalkylated ketones and aldehydes in isolated yields ranging from 39 to 76%. This procedure was successfully extended to the bis(methylthio)methylation with methyl (methylthio)methyl sulfoxide.

Selective Base-Catalyzed Rearrangement of Epoxides into Ketones. Application to γ-Keto Sulfide Synthesis

A methodology for the selective base-catalyzed isomerization of certain epoxides having a β-proton into ketones is presented. β,γ-Epoxy nitro compounds were the substrates for this transformation and underwent a multistep reaction consisting of epoxide ri

AN EPISULFONIUM ION MEDIATED RING EXPANSION OF 1-ALKENYLCYCLOALKANOLS

It has been found that TBDMS ethers of 1-alkenylcycloalkanols are readily rearranged to the ring expanded α-(1-phenylthioalkyl)cycloalkanones in high yields via episulfonoium ions.