51689-50-0

Usage

Derivative of

Benzaldehyde

Usage

Intermediate in the production of polymers, dyes, and pharmaceuticals

Physical state

Colorless liquid

Odor

Strong

Solubility

Insoluble in water, soluble in organic solvents

Industrial applications

Plastics, textiles, and pharmaceuticals

Role in synthesis

Building block for various compounds

Potential applications

Medical imaging and drug delivery due to unique chemical structure

Upstream product

• 69321-60-4 2,6-dibromotoluene 
• 68-12-2 N,N-dimethyl-formamide 
• 2317-22-8 2,6-dicyanotoluene 
• 55886-48-1 2-methylcyclohexa-2,5-diene-1-carboxylic acid 
• 4313-57-9 2,5-dihydrotoluene 

Downstream Products

• 66902-04-3 2-Methyl-5-nitroisophthalaldehyd 
• 51689-51-1 (2-methyl-1,3-phenylene)dimethanol 
• 1274751-19-7 3-(hydroxymethyl)-2-methylbenzaldehyde 
• 66901-98-2 2,6-Bis(brommethyl)benzol 
• 66902-05-4 2,6-Bis-(hydroxymethyl)-4-nitrotoluol 
• 73712-56-8 2,6-dicyano-α-deuteriotoluene 
• 41052-95-3 2,6-dicyano-1-ethylbenzene 
• 73712-55-7 N'-[1-[3-(Dimethyl-hydrazonomethyl)-2-methyl-phenyl]-meth-(E)-ylidene]-N,N-dimethyl-hydrazine 

Relevant academic research and scientific papers

Synthesis of an alkylthio-substituted dibenz[a,j]anthracene with improved solubility via the oxidative photocyclization of 1,3-distyrylbenzene derivatives

A series of 1,3-distyrylbenzene compounds bearing different substituents at the 2-position have been synthesized and subjected to an oxidative photocyclization process. The 1,3-distyrylbenzene compounds substituted with chloro, alkylthio, and diphenylphosphino groups at the 2-position afforded dibenz[a,j]anthracene derivatives, whereas those bearing methyl, trimethylsilyl, dimethylamino, butoxy, and fluoro groups gave benzo[c]chrysene derivatives. The solubility of dibenz[a,j]anthracene in organic solvents was improved by the introduction of alkylthio groups.

Total Synthesis of Hamigerans and Analogues Thereof. Photochemical Generation and Diels-Alder Trapping of Hydroxy-o-quinodimethanes

A number of naturally occurring substances, including hamigerans, contain ring systems which are fused to an aromatic nucleus. A general and streamlined method for the construction of such benzannulated bi- and polycyclic carbon frameworks has been develo

The synthesis of trianglimines: On the scope and limitations of the [3 + 3] cyclocondensation reaction between (1R,2R)-diaminocyclohexane and aromatic dicarboxaldehydes

The synthesis of aromatic dicarboxaldehydes, using dilithiation methodology is described along with their reactivity, in the [3 + 3] cyclocondensation reaction, with (1R,2R)-diaminocyclohexane to give trianglimine macrocycles. The scope and limitations of the cyclocondensation reaction are studied and some comments on the properties of the novel macrocycles are made such as their conformation in solution and temperature dependent dynamic NMR behaviour.

Vilsmeier Reaction on Some Alkyl-1,4-cyclohexadienes

Vilsmeier reaction on five alkyl-1,4-cyclohexadienes (I-V) has been studied.The structures of the resulting benzenedi- and tricarboxaldehydes (VII-XIII) have been assigned on spectral and elemental analyses data.

Conversion of 1,4-Dihydrobenzoic Acids to Polyformylbenzenes under Vilsmeier Reaction Conditions

1,4-Dihydrobenzoic acids 1a-e are converted by a one-pot reaction to benzene- mono-, di- and tricarboxaldehydes under Vilsmeier reaction conditions in yields ranging from 6 to 65percent.The same methodology also serves to give naphthalene-1,3-dicarboxaldehyde (2f) from 1,4-dihydro-1-naphthoic acid (1f) in 91percent yield.