51727-05-0

Basic information

• Product Name: 5,6-DIMETHYL-2-OXO-1,2-DIHYDRO-PYRIDINE-3-CARBOXYLIC ACID
• Synonyms: 5,6-DIMETHYL-2-OXO-1,2-DIHYDRO-PYRIDINE-3-CARBOXYLIC ACID;5,6-dimethyl-2-oxo-1,2-dihydropyridine-3-carboxylic acid(SALTDATA: FREE);2-Oxo-5,6-diMethyl-1,2-dihydro-3-pyridincarbonsaeure;2-hydroxy-5,6-diMethylnicotinic acid;5,6-DiMethyl-2-hydroxynicotinic acid;1,2-dihydro-5,6-diMethyl-2-oxopyridine-3-carboxylic acid;2-keto-5,6-dimethyl-1H-pyridine-3-carboxylic acid;5,6-dimethyl-2-oxo-1H-pyridine-3-carboxylic acid
• CAS NO: 51727-05-0
• Molecular Formula: C₈H₉NO₃
• Molecular Weight: 167.16
• Mol File: 51727-05-0.mol

Chemical Properties

• Boiling Point: 400.6 °C at 760 mmHg
• Flash Point: 196.1 °C
• Appearance: /
• Density: 1.268 g/cm³
• Vapor Pressure: 1.55E-07mmHg at 25°C
• Refractive Index: 1.538
• Storage Temp.: Inert atmosphere,Room Temperature
• PKA: 2.59±0.20(Predicted)
• CAS DataBase Reference: 5,6-DIMETHYL-2-OXO-1,2-DIHYDRO-PYRIDINE-3-CARBOXYLIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 5,6-DIMETHYL-2-OXO-1,2-DIHYDRO-PYRIDINE-3-CARBOXYLIC ACID(51727-05-0)
• EPA Substance Registry System: 5,6-DIMETHYL-2-OXO-1,2-DIHYDRO-PYRIDINE-3-CARBOXYLIC ACID(51727-05-0)

Safety Data

• Hazard Codes: Xi
• WGK Germany: 3
• HazardClass: IRRITANT
• Hazardous Substances Data: 51727-05-0(Hazardous Substances Data)

Usage

Uses

Used in Nutritional Supplements:
5,6-DIMETHYL-2-OXO-1,2-DIHYDRO-PYRIDINE-3-CARBOXYLIC ACID is used as a dietary supplement to prevent or treat niacin deficiency. It helps maintain optimal levels of this essential vitamin in the body, supporting various metabolic processes and overall health.
Used in Food Industry:
In the food industry, 5,6-DIMETHYL-2-OXO-1,2-DIHYDRO-PYRIDINE-3-CARBOXYLIC ACID is used as a nutrient to fortify various food products. It ensures that the products meet the recommended daily intake of niacin, contributing to the overall nutritional value of the food.
Used in Pharmaceutical Industry:
5,6-DIMETHYL-2-OXO-1,2-DIHYDRO-PYRIDINE-3-CARBOXYLIC ACID is used in the pharmaceutical industry for the development of medications that address niacin deficiency and its associated symptoms. It is also used in combination with other vitamins and minerals to create multivitamin formulations.
Used in Research:
In the field of research, 5,6-DIMETHYL-2-OXO-1,2-DIHYDRO-PYRIDINE-3-CARBOXYLIC ACID is used to study its role in various biological processes, such as energy metabolism, DNA repair, and the maintenance of healthy tissues. It also serves as a subject of investigation for potential therapeutic applications in the treatment of various health conditions.
Used in Cosmetics:
5,6-DIMETHYL-2-OXO-1,2-DIHYDRO-PYRIDINE-3-CARBOXYLIC ACID is used in the cosmetics industry for its skin health benefits. It is incorporated into skincare products to promote healthy skin and improve the appearance of skin conditions such as acne, eczema, and dermatitis.

InChI:InChI=1/C8H9NO3/c1-4-3-6(8(11)12)7(10)9-5(4)2/h3H,1-2H3,(H,9,10)(H,11,12)

Upstream product

• 72716-80-4 2-hydroxy-5,6-dimethylnicotinonitrile 
• 90007-21-9 2-hydroxy-5,6-dimethyl-nicotinic acid amide 
• 82756-27-2 2-amino-5,6-dimethyl-nicotinic acid 
• 58483-99-1 2-amino-5,6-dimethyl-nicotinamide 
• 22428-91-7 2-methyl-3-oxobutanal 
• 76544-67-7 2-amino-5,6-dimethyl-nicotinic acid ethyl ester 
• 143193-92-4 sodium 2‐methyl‐3‐oxobut‐1‐en‐1‐olate 
• 72716-80-4 1,2-dihydro-5,6-dimethyl-2-oxo-3-pyridinecarbonitrile 

Downstream Products

• 27992-31-0 5,6-dimethyl-pyridin-2-ol 
• 583-61-9 2,3-Lutidine 

Relevant articles and documents

Preparation process of 5,6-dimethyl-2-hydroxynicotinic acid

The invention provides a preparation process of 5,6-dimethyl-2-hydroxynicotinic acid 1. The preparation process of 5,6-dimethyl-2-hydroxynicotinic acid comprises the following steps: 1) performing a reaction on 2-butanone and ethyl formate in a proper solvent, under the existence of alkali and at proper temperature to obtain a compound 2; 2) performing condensation on the compound 2 and cyanoacetamide in a proper solvent and at proper temperature to obtain a compound 3; and 3) performing cyan-hydrolysis on the compound 3 under the existence of diluted acid to obtain 5,6-dimethyl-2-hydroxynicotinic acid 1. The synthesis route is as shown in the description. In the preparation process, the raw materials, the reagents and the solvents are the conventional synthesis reagents, and are cheap andeasily available; and the reaction condition of each step is mild, the aftertreatment operation is simple, the reaction yield is high and the product purity is high. The whole preparation cost of theproducts is low and the industrial production requirement is met.

Use of selected pyridone carboxamides or salts thereof as active substances against abiotic plant stress

The invention relates to the use of selected pyridone carboxamides or salts thereof as active substances against abiotic plant stress. The invention also relates to the use of substituted pyridone carboxamides of general formula (I) or the salts thereof, the groups in general formula (I) corresponding to the definitions cited in the description, for increasing the stress tolerance of plants to abiotic stress, for strengthening plant growth and/or for increasing the plant yield. The invention further relates to specific methods for producing said compounds.