22428-91-7

Usage

Uses

Used in Food Industry:
2-Formyl-3-butanone is used as a flavoring agent for its distinctive buttery aroma and taste, enhancing the flavor profiles of various food products.
Used in Fermentation Processes:
Diacetyl is a natural byproduct of fermentation and contributes to the characteristic flavors found in foods such as butter, cheese, and wine, adding depth and complexity to their taste.
However, due to health concerns associated with diacetyl, its use in food products has been regulated and reduced, leading to the exploration of alternative flavoring agents that can replicate its buttery notes without the associated risks.

InChI:InChI=1/C5H8O2/c1-4(3-6)5(2)7/h3-4H,1-2H3

Upstream product

• 78-93-3 butanone 
• 109-94-4 formic acid ethyl ester 
• 39925-74-1 3-(dodecylthiomethyl)-butanon-2 
• 1679-40-9 3-chloro-2-methyl-2-butenal 
• 2802-08-6 (E)-4-(dimethylamino)but-3-en-2-one 
• 74-88-4 methyl iodide 
• 71-43-2 benzene 
• 1190-91-6 4-dimethylamino-3-buten-2-one 

Downstream Products

• 36075-03-3 4,4-dimethoxy-3-methylbutan-2-one 
• 857950-59-5 N-acetyl-sulfanilic acid-(4,5-dimethyl-pyrimidin-2-ylamide) 
• 1193-74-4 4,5-dimethylpyrimidin-2-amine 
• 3354-39-0 4,5-dimethyl-1,2-dithiole-3-thione 
• 51479-87-9 3-methyl-4-methylamino-but-3-en-2-one 
• 72716-80-4 2-hydroxy-5,6-dimethylnicotinonitrile 
• 13732-32-6 biacetyl phenylhydrazone 
• 64-18-6 formic acid 
• 78-93-3 butanone 
• 63446-82-2 ethyl 3-methyl-4-oxocyclohex-2-enecarboxylate 
• 2199-45-3 4,5-dimethyl-pyrrole-2-carboxylic acid ethyl ester 
• 583-61-9 2,3-Lutidine 
• 51727-05-0 5,6-dimethyl-2-hydroxynicotinic acid 
• 27992-31-0 5,6-dimethyl-pyridin-2-ol 

Relevant academic research and scientific papers

Cassis and Green Tea: Spontaneous Release of Natural Aroma Compounds from β-Alkylthioalkanones

In depth headspace analysis of the slow degradation of β-alkylthioalkanones in ambient air led to the discovery of a novel δ-cleavage pathway, by which β-mercaptoketones are released. Since β-mercaptoketones are potent natural aroma compounds occurring in many fruits, herbs and flowers, the discovery of an enzyme-independent molecular precursor for this class of high-impact molecules is of practical importance. Moreover, the formation of β-diketones and aldehydes by concomitant oxidation at the α-sulfur-position enhances the versatility of this class of aroma precursors. A mechanistic model is proposed which suggests that the oxidative degradation occurs through a novel Pummerer-type rearrangement of initially formed persulfoxides.

Preparation process of 5,6-dimethyl-2-hydroxynicotinic acid

The invention provides a preparation process of 5,6-dimethyl-2-hydroxynicotinic acid 1. The preparation process of 5,6-dimethyl-2-hydroxynicotinic acid comprises the following steps: 1) performing a reaction on 2-butanone and ethyl formate in a proper solvent, under the existence of alkali and at proper temperature to obtain a compound 2; 2) performing condensation on the compound 2 and cyanoacetamide in a proper solvent and at proper temperature to obtain a compound 3; and 3) performing cyan-hydrolysis on the compound 3 under the existence of diluted acid to obtain 5,6-dimethyl-2-hydroxynicotinic acid 1. The synthesis route is as shown in the description. In the preparation process, the raw materials, the reagents and the solvents are the conventional synthesis reagents, and are cheap andeasily available; and the reaction condition of each step is mild, the aftertreatment operation is simple, the reaction yield is high and the product purity is high. The whole preparation cost of theproducts is low and the industrial production requirement is met.

Efficient synthesis of an A-B-C-tricycle fragment for a structural model of tolyporphin

An efficient stereocontrolled synthesis of an A-B-C-tricycle fragment 7 for a structural model of tolyporphin 3 is described. All the rings were prepared from readily available starting materials. One of the two key steps is a selective ring-opening reaction of the lactone cycle in bicyclolactam-lactone 17 to cyanopyrrolidone 18, which introduces the chirality into synthetic compounds. The other key step is the combination of A ring with B-C-bicycle via a two-time Eschenmoser sulfide contraction. A-B-C-tricycle fragment 7 allows a new approach toward tolypophin compounds and other uroporphinoids.