51739-40-3

Basic information

• Product Name: α-naphthyl p-methoxyphenyl sulphone
• Synonyms: α-naphthyl p-methoxyphenyl sulphone
• CAS NO: 51739-40-3
• Molecular Weight: 298.362
• Mol File: 51739-40-3.mol

Chemical Properties

• CAS DataBase Reference: α-naphthyl p-methoxyphenyl sulphone(CAS DataBase Reference)
• NIST Chemistry Reference: α-naphthyl p-methoxyphenyl sulphone(51739-40-3)
• EPA Substance Registry System: α-naphthyl p-methoxyphenyl sulphone(51739-40-3)

Safety Data

• Hazardous Substances Data: 51739-40-3(Hazardous Substances Data)

Upstream product

• 696-62-8 para-iodoanisole 
• 63735-42-2 sodium naphthalen-2-ylsulfinate 
• 696-63-9 4-Methoxybenzenethiol 
• 28912-93-8 1-naphthyldiazonium tetrafluoroborate 
• 91-20-3 naphthalene 
• 98-68-0 4-methoxy-phenyl-sulphonyl chloride 
• 51739-38-9 (4-methoxyphenyl) (naphthalen-1-yl)sulfane 

Downstream Products

• 97218-22-9 4-(naphthalen-1-ylsulfonyl)phenol 

Relevant articles and documents

Visible-Light Photoredox/Nickel Dual Catalysis for the Cross-Coupling of Sulfinic Acid Salts with Aryl Iodides

An efficient cross-coupling of sodium or lithium sulfinates with aryl iodides, using a combination of nickel and photoredox catalysis, is described. The dual catalyst system enables a versatile synthesis of aryl sulfones at room temperature in good yields and displays a broad functional group compatibility. The potential utility of this method in the late-stage diversification of complex molecules and in the conversion of organolithium reagents and sulfur dioxide into sulfones is demonstrated.

Visible-Light-Driven Silver-Catalyzed One-Pot Approach: A Selective Synthesis of Diaryl Sulfoxides and Diaryl Sulfones

An efficient one-pot approach for the synthesis of diaryl sulfoxides and diaryl sulfones using aryl thiols and aryl diazonium salts was developed. The use of a visible-light-driven silver catalysis and the subsequent singlet-oxygen-induced oxidation enabled selective synthesis of sulfoxides and sulfones in the absence of a photocatalyst. The reactions were carried out under mild reaction conditions; the desired products were obtained under air atmosphere at room temperature.

Visible-light-promoted synthesis of diaryl sulfides under air

A convergent, organocatalytic visible-light-mediated process for the synthesis of diaryl sulfides has been developed. A broad range of aryl thiols reacted with various aryl diazonium salts in the presence of eosin Y under air atmosphere to afford the desired diaryl sulfides in high yields. This novel and environmentally friendly method provides an alternative route to established synthetic approaches.

A KINETIC STUDY OF THE FRIEDEL-CRAFTS REACTION OF NAPHTHALENE WITH PARA- SUBSTITUTED BENZENESULPHONYL CHLORIDES: THE EFFECT OF THE SUBSTITUENT

The kinetics of the Friedel-Crafts reaction of naphthalene with para-substituted benzenesulphonyl chlorides have been investigated.The rate constants for equations (i) (formation of the sulphonyl cation) and (ii) (sulphone formation) were determined separately.The effect of the para-substituents on k1 was XC6H4SO2Cl + AlCl3 XC6H4SO2+*AlCl4- , XC6H4SO24*AlCl4- + C10H8 XC6H4SO2C10H7*AlCl3 + HCl well expressed by Yukawa-Tsuno equation, log(k1X/K1H)= ρ1(Δ?R(+))> where ρ1= -2.7 and γ1= 0.4.On the other hand, the effect of the para-substituents on k3(=k1k2/k-1) was expressed by the Brown-Okamoto equation, log(k3X/k3H)= ρ3?+ where ρ3= -2.8.Thus, the electron-donating para-substituents gave the greater reaction rates.We concluded that the sulphonyl cation gives large negative ρ values as a result of its high reactivity, and that its low selectivity for α-attack is due to a steric effect.These kinetic results have been rationalised in terms of bifunctional acid-base catalysis in phenylsulphonnylation.