51744-66-2

Basic information

• Product Name: 5,6-trans-Ergocalciferol
• Synonyms: (3β,5E,7E,22E)-9,10-Secoergosta-5,7,10(19),22-tetraen-3-ol;5,6-trans-Ergocalciferol;5,6-trans-VitaMin D2
• CAS NO: 51744-66-2
• Molecular Formula: C₂₈H₄₄O
• Molecular Weight: 396.64836
• Product Categories: Intermediates & Fine Chemicals;Metabolites & Impurities;Pharmaceuticals
• Mol File: 51744-66-2.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 5,6-trans-Ergocalciferol(CAS DataBase Reference)
• NIST Chemistry Reference: 5,6-trans-Ergocalciferol(51744-66-2)
• EPA Substance Registry System: 5,6-trans-Ergocalciferol(51744-66-2)

Safety Data

• Hazardous Substances Data: 51744-66-2(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
5,6-trans-Ergocalciferol is used as an intermediate compound for the synthesis of various Vitamin D analogs. Its structural properties make it a valuable precursor in the development of new drugs targeting conditions related to Vitamin D deficiency or metabolism.
Used in Nutritional Supplements:
5,6-trans-Ergocalciferol is used as an additive in the formulation of nutritional supplements, particularly those aimed at addressing Vitamin D-related health issues. Its presence in these supplements can help improve the bioavailability and effectiveness of Vitamin D in the human body.
Used in Research and Development:
In the field of research, 5,6-trans-Ergocalciferol serves as a crucial compound for studying the effects of Vitamin D on various biological processes. Its unique properties allow scientists to investigate the mechanisms of Vitamin D action and develop targeted therapies for related health conditions.
Used in Cosmetics Industry:
5,6-trans-Ergocalciferol is also utilized in the cosmetics industry, where it is employed as an active ingredient in skincare products. Its role in these products is to support skin health and promote the maintenance of healthy skin cells, potentially contributing to anti-aging effects and improved skin texture.

Upstream product

• 50-14-6 ergocalciferol 
• 87407-73-6 (S)-3-[(1R,3aS)-7a-Methyl-1-((E)-(1R,4R)-1,4,5-trimethyl-hex-2-enyl)-octahydro-inden-(4E)-ylidenemethyl]-2,2-dioxo-2,3,4,5,6,7-hexahydro-1H-2λ⁶-benzo[c]thiophen-5-ol 
• 70005-45-7 ergosta-5,7,22-trien-3β-ol 
• 13482-22-9 4-hydroxycyclohexanone 
• 87680-65-7 (S)-3-[(1R,3aS,7aR)-7a-Methyl-1-((E)-(1R,4R)-1,4,5-trimethyl-hex-2-enyl)-octahydro-inden-(4E)-ylidenemethyl]-2,2-dioxo-2,3,4,5,6,7-hexahydro-1H-2λ⁶-benzo[c]thiophen-5-ol 
• 85925-89-9 (5E)-10-Oxo-19-norergocalciferol 
• 19493-09-5 Methylenetriphenylphosphorane 
• 60-29-7 diethyl ether 
• 50-14-6 Calciferol 

Downstream Products

• 87407-73-6 (S)-3-[(1R,3aS)-7a-Methyl-1-((E)-(1R,4R)-1,4,5-trimethyl-hex-2-enyl)-octahydro-inden-(4E)-ylidenemethyl]-2,2-dioxo-2,3,4,5,6,7-hexahydro-1H-2λ⁶-benzo[c]thiophen-5-ol 
• 54573-75-0 1α-hydroxyergocalciferol 
• 104846-62-0 tert-Butyl-dimethyl-{(S)-4-methylene-3-[2-[(1R,3aS)-7a-methyl-1-((E)-(1R,4R)-1,4,5-trimethyl-hex-2-enyl)-octahydro-inden-(4E)-ylidene]-eth-(E)-ylidene]-cyclohexyloxy}-silane 
• 50-14-6 (S)-4-Methylene-3-[2-[(1R,3aS)-7a-methyl-1-((E)-(1R,4R)-1,4,5-trimethyl-hex-2-enyl)-octahydro-inden-(4E)-ylidene]-eth-(E)-ylidene]-cyclohexanol 
• 112670-78-7 (1S,5R)-5-(tert-Butyl-dimethyl-silanyloxy)-2-methylene-3-[2-[(R)-7a-methyl-1-((E)-(1R,4R)-1,4,5-trimethyl-hex-2-enyl)-octahydro-inden-(4E)-ylidene]-eth-(Z)-ylidene]-cyclohexanol 
• 112670-78-7 (1S,5R)-5-(tert-Butyl-dimethyl-silanyloxy)-2-methylene-3-[2-[(1R,3aS)-7a-methyl-1-((E)-(1R,4R)-1,4,5-trimethyl-hex-2-enyl)-octahydro-inden-(4E)-ylidene]-eth-(E)-ylidene]-cyclohexanol 
• 367487-78-3 [3S-(1E,3β,5α)]-[3-fluoro-5-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-2-methylenecyclohexylidene]ethanol 
• 1014718-14-9 C₃₇H₅₉⁽²⁾H₆FO₂Si₂ 
• 1014718-19-4 1α-tert-butyl-dimethyl-silanyloxy-3β-fluoro-25-trimethylsilanyloxy-16-ene-20-cyclopropyl-26,27-hexadeutero-cholecalciferol 
• 199798-99-7 C₃₈H₆₅FO₂Si₂ 
• 1014717-86-2 C₄₅H₆₉⁽²⁾H₆F₇O₃Si₃ 
• 1014717-93-1 C₄₅H₆₉⁽²⁾H₆F₇O₃Si₃ 
• 1014717-90-8 C₄₅H₇₁⁽²⁾H₆F₇O₃Si₃ 
• 1014718-06-9 C₄₅H₇₁⁽²⁾H₆F₇O₃Si₃ 

Relevant articles and documents

Hydrotitanation-Protonation of Vitamin D2 and Its Analogues: An Efficient Method for the Preparation of 10,19-Dihydrovitamins D2 Including Dihydrotachysterol2

In this study we describe an easy and efficient method for the preparation of the known 10,19-dihydrovitamins D2 2b (DHV2-II), 2c (DHV2-IV), 3c (dihydrotachysterol2, DHT2), and the new dihydrovitamins D2 2f and 2g.This method is based on the regioselective hydrometalation reaction of vitamin D2 and its derivatives with the system Cp2TiCl2-LiAlH4 or Cp2TiCl2-Red-Al (Aldrich).Under optimal conditions, the reaction with the former of these hydrometalating systems takes place with a high degree of stereoselectivity and allows labelling at C-19.