51748-25-5Relevant academic research and scientific papers
Transition-Metal-Free ipso-Trifluoromethylthiolation of Lithium Aryl Boronates
Shen, Feng,Zheng, Hanliang,Xue, Xiao-Song,Lu, Long,Shen, Qilong
, p. 6347 - 6351 (2019/08/20)
A transition-metal-free direct trifluoromethylthiolation of the ipso-carbon of lithium aryl boronates with trifluoromethanesulfenate under mild conditions was described. In addition, late-stage site-selective C-H borylation/trifluoromethylation and C-Cl b
Synthesis and Reactivity of α-Cumyl Bromodifluoromethanesulfenate: Application to the Radiosynthesis of [18F]ArylSCF3
Wu, Jiang,Zhao, Qunchao,Wilson, Thomas C.,Verhoog, Stefan,Lu, Long,Gouverneur, Véronique,Shen, Qilong
, p. 2413 - 2417 (2019/02/01)
A highly reactive electrophilic bromodifluoromethylthiolating reagent, α-cumyl bromodifluoro-methanesulfenate 1, was prepared to allow for direct bromodifluoromethylthiolation of aryl boron reagents. This coupling reaction takes place under copper catalysis, and affords a large range of bromodifluoromethylthiolated arenes. These compounds are amenable to various transformations including halogen exchange with [18F]KF/K222, a process giving access to [18F]arylSCF3 in two steps from the corresponding aryl boronic pinacol esters.
Phenylethylamine derivatives
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, (2008/06/13)
Trifluoromethylthiophenylethylamine derivatives, made from the corresponding acid chlorides by successive reduction, condensation with nitroethane, reduction, and condensation with an amine, possess anorexigenic properties, unaccompanied by central stimulant activity or cardiovascular effects.
Phenyl propanones
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, (2008/06/13)
Trifluoromethylthiophenylethylamine derivatives, made from the corresponding acid chlorides by successive reduction, condensation with nitroethane, reduction, and condensation with an amide, possess anorexigenic properties, unaccompanied by central stimulant activity or cardiovascular effects.
