51768-59-3Relevant academic research and scientific papers
Isolation of a High-Affinity Cannabinoid for the Human CB1 Receptor from a Medicinal Cannabis sativa Variety: Δ9-Tetrahydrocannabutol, the Butyl Homologue of Δ9-Tetrahydrocannabinol
Belardo, Carmela,Cannazza, Giuseppe,Citti, Cinzia,Forni, Flavio,Gigli, Giuseppe,Laganà, Aldo,Linciano, Pasquale,Luongo, Livio,Maione, Sabatino,Montone, Carmela Maria,Vandelli, Maria Angela
, (2020)
The butyl homologues of Δ9-tetrahydrocannabinol, Δ9-tetrahydrocannabutol (Δ9-THCB), and cannabidiol, cannabidibutol (CBDB), were isolated from a medicinal Cannabis sativa variety (FM2) inflorescence. Appropriate spectrosco
CANNABIS EXTRACTS AND USES THEREOF
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, (2022/03/14)
The present disclosure concerns a group of cannabinoid compounds defined by formulas (I) to (IV), wherein R1 is —H or —COOH, for the first time isolated and fully characterized in structure, absolute stereochemistry by the present applicant. Methods of isolation, characterization, stereoselective synthesis, biological activity, pharmaceutical compositions and therapeutic applications of the present compounds as modulators of the cannabinoid CB1 receptor are also object of the disclosure.
