51779-50-1

Upstream product

• 98-88-4 benzoyl chloride 
• 79-08-3 bromoacetic acid 
• 75-05-8 acetonitrile 
• 60050-48-8 3-benzamido-2-butenoic acid ethyl ester 
• 107465-72-5 5-(1-benzoylaminoethylidene)-2,2-dimethyl-1,3-dioxane-4,6-dione 
• 60050-42-2 (4-methyl-5-oxo-2-phenyl-4,5-dihydro-oxazol-4-yl)-acetic acid ethyl ester 

Downstream Products

• 13514-79-9 6-methyl-2-phenyl-3H-pyrimidin-4-one 
• 76569-86-3 1-Methyl-5-phenyl-2-oxa-6-aza-bicyclo[2.2.0]hex-5-en-3-one 
• 76569-84-1 2-methyl-4-phenyl-6H-1,3-oxazin-6-one 
• 20959-22-2 3,6-dimethyl-2-phenylpyrimidine-4(3H)-one 
• 46181-30-0 6-methyl-2-phenylpyridine 

Relevant academic research and scientific papers

1,3-Oxazines and Related Compounds. XII. Facile Synthesis of 2,4-Disubstituted 6H-1,3-Oxazin-6-ones

A convenient method for synthesis of 2,4-disubstituted 6H-1,3-oxazin-6-ones (8) was developed.Acylaminoalkylidene-1,3-dioxane-4,6-diones (5a-l), which were prepared from N-acylimidates (3a-l) and Meldrum's acid (4), readily underwent thermolysis upon heating, leading to a variety of 2,4-disubstituted 6H-1,3-oxazin-6-ones (8a-l).Keywords - 6H-1,3-oxazin-6-one; Meldrum's acid; acylaminoalkylidene-1,3-dioxane-4,6-dione; N-acylimidate; thermolysis

Observation of two oxa-azabicyclohexenone intermediates along the reaction pathway of the photochemical isomerization of 1,3-oxazin-6-ones

Irradiation of 4-methyl-2-phenyl-1,3-oxazin-6-one, 1, yields a photochemical equilibrium between 1 and 2-methyl-4-phenyl-1,3-oxazin-6-one, 2.The isomerization proceeds through two intermediates, the oxa-azabicyclohexenones 3 and 4, both of which can be observed spectroscopically (ir, uv, 1H nmr) at low temperature.