51787-75-8Relevant academic research and scientific papers
Improvement of ways to obtain ethidium bromide and synthesis of ethidium ethyl sulfate, a new fluorescent dye for detection of nucleic acids
Osadchii,Shubin,Kozlova,Varlamenko,Filipenko,Boyarskikh
scheme or table, p. 1541 - 1548 (2012/01/14)
Two methods for synthesis of ethidium bromide, a fluorescent dye widely used in molecular biology, were improved. An analog of ethidium bromide, ethidium ethyl sulfate, was synthesized.
SYNTHESE DANS LA CHIMIE DES PHENANTHRIDINES. III. PREPARATION DE QUELQUES MODELES D'ACIDES ω-(DIAMINO-3,8 PHENANTHRIDINYL-6) CARBOXYLIQUES
Lion, C.,Boukou-Poba, J. P.,Charvy, C.
, p. 171 - 181 (2007/10/02)
New series of ω-(3,8-diamino-6-phenanthridinyl) alkanoic acids are obtained from the acid chloride-esters ROCO(CH2)nCOCl (n =0, 3 to 8; R = Me or Et).Reaction of these with 2-amino-3,8-dicarbethoxyaminobiphenyl leads to the expected 2-acylamino-3,8-dicarbethoxyaminobiphenyls which by cyclization lead to the corresponding methyl or ethyl (3,8-dicarbethoxyamino-6-phenanthridinyl)alkanoates.Quaternarization followed by hydrolysis has been performed to obtain some ω-(3,8-diamino-6-phenanthridinium) alkanoic acid salts.
