6272-52-2

Basic information

• Product Name: 4'-NITRO-BIPHENYL-2-YLAMINE
• Synonyms: 2-amino-4’-nitrobiphenyl;4’-nitro-2-biphenylamin;4'-NITRO-BIPHENYL-2-YLAMINE;4'-nitro-[1,1'-biphenyl]-2-amine;[1,1'-Biphenyl]-2-amine,4'-nitro-
• CAS NO: 6272-52-2
• Molecular Formula: C₁₂H₁₀N₂O₂
• Molecular Weight: 214.22
• EINECS: 228-462-0
• Mol File: 6272-52-2.mol
• Article Data: 11

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4'-NITRO-BIPHENYL-2-YLAMINE(CAS DataBase Reference)
• NIST Chemistry Reference: 4'-NITRO-BIPHENYL-2-YLAMINE(6272-52-2)
• EPA Substance Registry System: 4'-NITRO-BIPHENYL-2-YLAMINE(6272-52-2)

Safety Data

• Hazardous Substances Data: 6272-52-2(Hazardous Substances Data)

Usage

General Description

4'-Nitro-biphenyl-2-ylamine is a chemical compound that belongs to the group of nitroaryl amines. It is commonly used in the synthesis of drugs, dyes, and agricultural chemicals. 4'-NITRO-BIPHENYL-2-YLAMINE has been identified as a potential human carcinogen and is a known mutagen. It is also considered to be toxic to aquatic organisms and may cause long-term adverse effects in the aquatic environment. Due to its hazardous nature, proper handling and disposal techniques must be employed when working with 4'-nitro-biphenyl-2-ylamine to mitigate the risk of exposure and environmental contamination.

Upstream product

• 606-81-5 2,4'-dinitrobiphenyl 
• 625-58-1 ethyl nitrate 
• 90-41-5 2-phenylaniline 
• 7664-93-9 sulfuric acid 
• 24067-17-2 4-nitrophenylboronic acid 
• 615-36-1 2-bromoaniline 
• 586-78-7 para-nitrophenyl bromide 
• 191171-55-8 2-anilineboronic acid pinacol ester 
• 98-80-6 phenylboronic acid 
• 148493-54-3 tributyl (o-tert-butyloxycarbonylaminophenyl) stannane 
• 3422-01-3 tert-butyl phenylcarbamate 
• 636-98-6 p-nitrobenzene iodide 
• 185408-20-2 o-(tributylstannyl)aniline 
• 615-43-0 2-iodophenylamine 

Downstream Products

• 114617-88-8 (4'-nitro-biphenyl-2-yl)-phenyl-phosphinic acid 
• 154019-57-5 4-(4'-Nitro-biphenyl-2-yl)-4H-[1,2,4]triazole 
• 106589-02-0 2-amino>isophthalic acid 
• 146231-71-2 N-(4'-Nitro-biphenyl-2-yl)-2-{4-[(4'-nitro-biphenyl-2-ylcarbamoyl)-methyl]-phenyl}-acetamide 
• 944457-70-9 [2-(1H-indol-3-yl)-1-(4'-nitro-biphenyl-2-ylcarbamoyl)ethyl]carbamic acid tert-butyl ester 
• 1006872-22-5 C₂₆H₂₇N₃O₅ 
• 944457-73-2 C₃₃H₃₃N₃O₆ 
• 97388-37-9 4,4'''-dinitro-o-quaterphenyl 
• 94764-55-3 3-nitrodibenzo[b,d]thiophene 
• 412337-65-6 N-(4'-nitro-biphenyl-2-yl)-benzamide 
• 845895-81-0 nicotinic acid-(4'-nitro-biphenyl-2-ylamide) 
• 51787-75-8 4,4'-dinitro-2-biphenylamine 
• 81316-79-2 2-nitrotriphenylene 
• 14191-22-1 2-nitrocarbazole 

Relevant articles and documents

Analysis of the Orbital and Electrostatic Contributions to the Lone Pair-Aromatic Interaction Using Molecular Rotors

The attractive interaction between carbonyl oxygens and the π-face of aromatic surfaces was studied using N-phenylimide molecular rotors. The C=O···Ar interactions could stabilize the transition states but were half the strength of comparable C=O···C=O interactions. The C=O···Ar interaction had a significant electrostatic component but only a small orbital delocalization component.

Atmosphere-Controlled Palladium-Catalyzed Divergent Decarboxylative Cyclization of 2-Iodobiphenyls and α-Oxocarboxylic Acids

A novel palladium-catalyzed divergent decarboxylative cyclization of 2-iodobiphenyls and α-oxocarboxylic acids utilizing the atmosphere as a controlled switch is reported. Under the protection of a nitrogen atmosphere, tribenzotropones are synthesized by a [4 + 3] decarboxylative cyclization. Employing a palladium/O2 system enables a [4 + 2] decarboxylative cyclization to assemble triphenylenes. Notably, preliminary mechanistic studies indicate that the formation of triphenylenes involves a double decarboxylation.

Cyclization of 2-Biphenylthiols to Dibenzothiophenes under PdCl2/DMSO Catalysis

A palladium-catalyzed synthesis of dibenzothiophenes from 2-biphenylthiols is described. This highly efficient reaction employs a simple PdCl2/DMSO catalytic system, in which PdCl2 is the sole metal catalyst and DMSO functions as an oxidant and solvent. This transformation has broad substrate scope and operational simplicity and proceeds in high yield. The synthetic utility was demonstrated by the facile synthesis of helical dinapthothiophene 3 and an eminent organic semiconductor DBTDT 4. Importantly, highly strained trithiasumanene 5, a buckybowl of considerable synthetic challenge, was observed under this catalytic system.