51788-87-5

Basic information

• Product Name: 2-bromo-4-fluoro-1-(prop-1-en-2-yl)benzene
• Synonyms: 2-bromo-4-fluoro-1-(prop-1-en-2-yl)benzene
• CAS NO: 51788-87-5
• Molecular Weight: 215.065
• Mol File: 51788-87-5.mol
• Article Data: 10

Chemical Properties

• CAS DataBase Reference: 2-bromo-4-fluoro-1-(prop-1-en-2-yl)benzene(CAS DataBase Reference)
• NIST Chemistry Reference: 2-bromo-4-fluoro-1-(prop-1-en-2-yl)benzene(51788-87-5)
• EPA Substance Registry System: 2-bromo-4-fluoro-1-(prop-1-en-2-yl)benzene(51788-87-5)

Safety Data

• Hazardous Substances Data: 51788-87-5(Hazardous Substances Data)

Upstream product

• 917-64-6 methyl magnesium iodide 
• 1006-39-9 1-(2-bromo-4-fluorophenyl)ethanone 
• 1073-06-9 3-fluorobromobenzene 
• 1006-41-3 2-bromo-4-fluorobenzoic acid 
• 653-92-9 methyl 2-bromo-4-fluorobenzoate 
• 51788-83-1 2-(2-bromo-4-fluorophenyl)propan-2-ol 
• 1779-49-3 Methyltriphenylphosphonium bromide 
• 261711-20-0 1-(2-bromo-4-fluorophenyl)ethan-1-ol 
• 59142-68-6 2-bromo-4-fluorobenzaldehyde 

Downstream Products

• 1241898-33-8 2-bromo-4-fluoro-1-(1-methylcyclopropyl)benzene 
• 1610833-58-3 3-(2-bromo-4-fluorophenyl)-3-methylcyclobutan-1-one 

Relevant articles and documents

Ene reactions of 2-borylated α-methylstyrenes: A practical route to 4-methylenechromanes and derivatives

4-Methylenechromanes were prepared via a three-step process from 2-borylated α-methylstyrenes. This sequence is based on a key glyoxylate-ene reaction catalyzed by scandium(iii) triflate. The resulting γ-hydroxy boronates, which cyclise to seven-membered

Asymmetric Synthesis and Application of Chiral Spirosilabiindanes

Reported here is the development of a class of chiral spirosilabiindane scaffolds by Rh-catalyzed asymmetric double hydrosilation, for the first time. Enantiopure SPSiOL (spirosilabiindane diol), a new type of chiral building block for the preparation of various chiral ligands and catalysts, was readily prepared on greater than 10 gram scale using this protocol. The potential of this new spirosilabiindane scaffold in asymmetric catalysis was preliminarily demonstrated by development of the corresponding monodentate phosphoramidite ligands (SPSiPhos), which were used in both a Rh-catalyzed hydrogenation and a Pd-catalyzed intramolecular carboamination.

Pd-Catalyzed Enantioselective Ring Opening/Cross-Coupling and Cyclopropanation of Cyclobutanones

A palladium-catalyzed enantioselective sequential ring-opening/cross-coupling of cyclobutanones is disclosed that provides chiral indanones bearing C3-quaternary stereocenters. The reaction process involves palladium-catalyzed nucleophilic addition of cyc