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(E)-1-(Pentamethoxyphenyl)-3-phenyl-2-propen-1-one, also known as 2'-Hydroxy-4'-Methoxychalcone, is a chalcone derivative with the molecular formula C20H20O5. It is a type of flavonoid compound characterized by a phenyl group, a propenone group, and five methoxy substituents attached to the phenyl ring. This chemical compound has garnered interest due to its potential antioxidant, anti-inflammatory, and anticancer properties, making it a promising candidate for research in medicinal chemistry and drug discovery.

518-58-1

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518-58-1 Usage

Uses

Used in Pharmaceutical Industry:
(E)-1-(Pentamethoxyphenyl)-3-phenyl-2-propen-1-one is used as a pharmaceutical candidate for its potential antioxidant, anti-inflammatory, and anticancer properties. Its ability to modulate various biological pathways and exhibit therapeutic effects makes it a valuable compound in the development of new drugs for the treatment of various diseases.
Used in Drug Discovery:
In the field of drug discovery, (E)-1-(Pentamethoxyphenyl)-3-phenyl-2-propen-1-one is utilized for its potential to contribute to the development of novel therapeutic agents. Its unique structure and biological activities are being investigated to identify new drug targets and enhance the efficacy of existing treatments.
Used in Antioxidant Applications:
(E)-1-(Pentamethoxyphenyl)-3-phenyl-2-propen-1-one is employed as an antioxidant agent, which can help protect cells from oxidative stress and damage caused by reactive oxygen species. Its antioxidant properties make it a potential candidate for use in the prevention and treatment of various diseases associated with oxidative stress.
Used in Anti-inflammatory Applications:
As an anti-inflammatory agent, (E)-1-(Pentamethoxyphenyl)-3-phenyl-2-propen-1-one can be used to modulate inflammatory responses and alleviate symptoms associated with inflammation. Its potential to target specific inflammatory pathways makes it a valuable compound in the development of new anti-inflammatory drugs.
Used in Anticancer Applications:
(E)-1-(Pentamethoxyphenyl)-3-phenyl-2-propen-1-one is being studied for its potential as an anticancer agent, with the ability to inhibit the growth and proliferation of cancer cells. Its mechanism of action may involve targeting specific signaling pathways and cellular processes, making it a promising candidate for the development of new cancer therapies.

Check Digit Verification of cas no

The CAS Registry Mumber 518-58-1 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 5,1 and 8 respectively; the second part has 2 digits, 5 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 518-58:
(5*5)+(4*1)+(3*8)+(2*5)+(1*8)=71
71 % 10 = 1
So 518-58-1 is a valid CAS Registry Number.
InChI:InChI=1/C20H22O6/c1-22-16-15(14(21)12-11-13-9-7-6-8-10-13)17(23-2)19(25-4)20(26-5)18(16)24-3/h6-12H,1-5H3/b12-11+

518-58-1Relevant academic research and scientific papers

A dihydrochalcone from Lindera lucida

Leong, Yuan-Wah,Harrison, Leslie J.,Bennett, Graham J.,Kadir, Azizol A.,Connolly, Joseph D.

, p. 891 - 894 (1998)

A new dihydrochalcone, 3',5'-dihydroxy-2',4',6'- trimethoxydihydrochalcone and five known compounds, methyl linderone, 5- hydroxy-6,7,8-trimethoxyflavone (alnetin), 2'-hydroxy-3',4',5',6'- tetramethoxydihydrochalcone (dihydrokanakugiol), 2'-hydroxy-3',4',5',6'- tetramethoxychalcone (kanakugiol) and 2',3',4',5',6'-pentamethoxychalcone (pedicellin) were isolated from twigs of Lindera lucida. The structures of these compounds were determined by spectral analyses and chemical correlations.

A CHALCONE AND FLAVANONES FROM DIDYMOCARPUS PEDICELLATA

Rathore, J. S.,Garg, S. K.,Gupta, S. R.

, p. 1755 - 1756 (1981)

Key Word Didymocarpus pedicellata; Gesneriaceae; 3'-hydroxy-2',4',5',6'-teramethoxychalcone; 5-hydroxy-6,7,8-trimethoxyflavanone; 6-hydroxy-5,7,8-trimethoxyflavanone; isopedicin; structural determination.

13C Nuclear Magnetic Resonance Studies on 1,3-Diphenylprop-2-enones

Parmar, V. S.,Sharma, Sunil,Rathore, J. S.,Garg, Meenu,Gupta, Sandhya,et al.

, p. 470 - 474 (2007/10/02)

The 13C NMR spectra of 48 differently substituted chalcones (1,3-diphenylprop-2-enones) have been recorded and the results are discussed.The data will be useful in the identification of new/natural chalcones.

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