14786-40-4

Basic information

• Product Name: Ethanone, 1-(pentamethoxyphenyl)-
• Synonyms: pentamethoxy-acetophenone;2',3',4',5',6'-pentamethoxyacetophenone
• CAS NO: 14786-40-4
• Molecular Formula: C13H18O6
• Molecular Weight: 270.282
• Mol File: 14786-40-4.mol

Chemical Properties

• CAS DataBase Reference: Ethanone, 1-(pentamethoxyphenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Ethanone, 1-(pentamethoxyphenyl)-(14786-40-4)
• EPA Substance Registry System: Ethanone, 1-(pentamethoxyphenyl)-(14786-40-4)

Safety Data

• Hazardous Substances Data: 14786-40-4(Hazardous Substances Data)

Upstream product

• 3162-28-5 2-hydroxy-3,4,5,6-tetramethoxyacetophenone 
• 91556-09-1 2,3,4,5,6-pentamethoxybenzoic acid 
• 75-16-1 methylmagnesium bromide 
• 92157-76-1 methyl 2,3,4,5,6-pentamethoxybenzoate 
• 74-88-4 methyl iodide 
• 478-01-3 nobiletin 
• 56002-81-4 1,2-dihydroxy-3,4,6-trimethoxybenzene 
• 6953-31-7 2'-acetoxy-3',4',5'-trimethoxyacetophenone 
• 7508-05-6 1-(2,3,4,6-tetramethoxyphenyl)ethanone 
• 7507-98-4 1-(2-hydroxy-3,4,6-trimethoxyphenyl)ethanone 
• 5333-45-9 1,2,3,5-tetramethoxybenzene 
• 530-55-2 2,6-dimethoxy-p-quinone 
• 15233-65-5 2,6-dimethoxy-1,4-hydroquinone 
• 13909-75-6 1,2,3,4,5-pentamethoxybenzene 

Downstream Products

• 1322640-36-7 C₂₇H₂₈O₉ 
• 29201-96-5 C₂₇H₂₈O₉ 
• 34810-62-3 3′-methoxy-4′-hydroxy-5,6,7,8-tetramethoxyflavone 
• 29201-97-6 4'-benzyloxy-3',5,6,7,8-pentamethoxyflavone 
• 29201-99-8 3'-benzyloxy-4',5,6,7,8-pentamethoxyflavone 
• 34810-60-1 2-(3-Methoxy-4-benzyloxy-benzoyloxy)-3,4,5,6-tetramethoxyacetophenon 
• 80140-31-4 3',4'-dihydroxy-5,6,7,8,-tetramethoxyflavone 
• 80140-30-3 3',4'-Dibenzyloxy-5,6,7,8-tetramethoxyflavone 
• 80140-29-0 2-Hydroxy-3',4'-dibenzyloxy-3,4,5,6-tetramethoxydibenzoylmethane 
• 80140-28-9 2-(3',4'-Dibenzyloxy)benzoyloxy-3,4,5,6-tetramethoxyacetophenone 
• 112448-39-2 2-(3-hydroxy-4-methoxyphenyl)-5,6,7,8-tetramethoxy-4H-1-benzopyran-4-one 
• 478-01-3 nobiletin 
• 1322640-35-6 C₂₇H₂₈O₉ 
• 67231-44-1 2,3,4,5,6-Pentamethoxybenzoylaceton 

Relevant articles and documents

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The microwave-assisted methylation of 2,5-dihydroxy-1,3-dimethoxybenzene with (CH3O)2SO2 for 5 min gave easily 1,2,3,5-tetramethoxybenzene, which was converted into pentamethoxybenzene. The microwave-assisted Friedel-Crafts acylation of pentamethoxybenzene in the presence of In(CF3SO3)3 gave pentamethoxyacetophenone for 15 min under solvent-free conditions in high yield. The microwave-assisted cyclization reaction of the diketones, which were synthesized from the acetophenone via three steps under microwave irradiation, gave the desired polymethoxyflavones for 1.5-3 min in high yields. The polymethoxyflavones showed inhibitory effects on melanogenesis in a human melanoma.

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