518-86-5

Usage

Uses

Used in Pharmaceutical Industry:
3H-2-Oxa-1H-phenalene-1-one is used as a building block for the synthesis of pharmaceutical drugs due to its versatile chemical structure and potential medicinal properties. Its presence in natural products and essential oils suggests a foundation for developing new therapeutic agents.
Used in Agrochemical Industry:
3H-2-Oxa-1H-phenalene-1-one is used as a component in the synthesis of agrochemicals, leveraging its chemical properties to create compounds that can be used in agricultural applications for pest control and crop protection.
Used in Organic Synthesis:
3H-2-Oxa-1H-phenalene-1-one is used as a key intermediate in organic synthesis for creating a variety of complex organic molecules. Its unique structure allows for the development of new compounds with potential applications in various fields.
Used in Research and Development:
3H-2-Oxa-1H-phenalene-1-one is utilized in research and development for studying its pharmaceutical properties, such as anti-inflammatory, anticancer, and antimicrobial activities. This research can lead to the discovery of new drugs and treatments for various diseases and conditions.

InChI:InChI=1/C12H8O2/c13-12-10-6-2-4-8-3-1-5-9(7-14-12)11(8)10/h1-6H,7H2

Upstream product

• 83-32-9 acenaphthene 
• 81-84-5 1,8-Naphthalic anhydride 
• 86-55-5 1-naphthalenecarboxylic acid 
• 74-95-3 1,1-dibromomethane 

Downstream Products

• 19310-98-6 8-methyl-1-naphthoic acid 
• 939026-04-7 (2'-hydroxymethyl-biphenyl-2-yl)diphenylmethanol 
• 90-12-0 1-Methylnaphthalene 
• 61886-71-3 1-ethyl-8-methylnaphthalene 
• 81603-44-3 1-isopropyl-8-methylnaphthalene 
• 81603-32-9 N-(2,4-Dinitro-phenyl)-N'-[1-(8-methyl-naphthalen-1-yl)-eth-(E)-ylidene]-hydrazine 
• 24018-02-8 7,7-diphenyl-7H-dibenz[c,e]oxepin-5-one 

Relevant academic research and scientific papers

Mild and efficient synthesis of 1,8-naphthalide and 1,8- naphthalenedimethanol

Mild and efficient procedures have been developed for synthesis of 1,8-naphthalide and 1,8-naphthalenedimethanol. In an ice-water bath, 1,8-naphthalide was prepared from 1,8-naphthlic anhydride using LiAlH 4 as reducing agent. 1,8-Naphthalenedi

Catalytic oxidation of acenaphthene and its derivatives in acetic acid

The chemistry of formation of products of acenaphthene oxidation in the presence of the catalyst containing both manganese and cobalt bromides under batch conditions is discussed. The main reaction products are acenaphthene quinone, acenaphthenol-9, trans-acenaphthylene glycol, naphthalide, and naphthalic anhydride. The sequence of reactions leading to the final products is established. It is shown that the main oxidation product in the presence of the manganese-based catalyst is naphthalic anhydride, and the main product in the presence of the cobalt-based catalyst is acenaphthene quinone. The process and engineering techniques providing for the high overall and fractional yields of the desired products are discussed.

1,8-NAPHTHALENECARBOLACTONE AND ACENAPHTHENONE IN THE LIQUID-PHASE OXIDATION OF ACENAPHTHENE TO NAPHTHALIC ANHYDRIDE

The yields and ratios of the intermediate products in the liquid-phase oxidation of acenaphthene by molecular oxygen in butyric acid in the absence of a catalyst and in the presence of cobalt and cobalt-manganese catalyst depend on the conditions of oxidation and on the nature of the catalyst.One of the main intermediate products in the oxidation of acenaphthene, i.e., 1,8-naphthalenecarbolactone, was isolated and identified.It can form at the early stages of the reaction in parallel with acenaphthenone.