518058-73-6Relevant articles and documents
Bicyclic compositions and methods for modulating a kinase cascade
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Page/Page column 73, (2008/06/13)
The invention relates to compounds and methods for modulating one or more components of a kinase cascade.
Protein kinase and phosphatase inhibitors and methods for designing them
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, (2008/06/13)
The present invention provides a method for identifying inhibitors of protein kinases and/or protein phosphatases. Methods are also provided for inhibiting protein kinase and/or protein phosphatase activity. Specific non-peptide protein tyrosine kinase and/or protein phosphatase inhibitors are provided. The protein kinase or protein phosphatase inhibitors of the present invention may be used to treat a number of conditions in patients, including cancer, psoriasis, arthrosclerosis, immune system activity, Type II diabetes, and obesity.