5181-10-2

Basic information

• Product Name: 4,4'-DICHLORO DIPHENYL SULFIDE
• Synonyms: 4,4'-DICHLORO DIPHENYL SULFIDE;1,1’-thiobis(4-chloro-benzen;1-Chloro-4-[(4-chlorophenyl)sulfanyl]benzene;4-Chlorophenyl sulfide;4-chlorophenylsulfide;Benzene, 1,1'-thiobis(4-chloro-;Benzene, 1,1'-thiobis*4-chloro-;Bis(4-chlorophenyl) sulfide
• CAS NO: 5181-10-2
• Molecular Formula: C₁₂H₈Cl₂S
• Molecular Weight: 255.16
• Mol File: 5181-10-2.mol
• Article Data: 136

Chemical Properties

• Melting Point: 88-89 °C
• Boiling Point: 379.927 °C at 760 mmHg
• Flash Point: 171.332 °C
• Appearance: /
• Density: 1.366 g/cm³
• CAS DataBase Reference: 4,4'-DICHLORO DIPHENYL SULFIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 4,4'-DICHLORO DIPHENYL SULFIDE(5181-10-2)
• EPA Substance Registry System: 4,4'-DICHLORO DIPHENYL SULFIDE(5181-10-2)

Safety Data

• Hazardous Substances Data: 5181-10-2(Hazardous Substances Data)

Usage

Synthesis Reference(s)

Synthetic Communications, 12, p. 903, 1982 DOI: 10.1080/00397918208065970Synthesis, p. 61, 1979 DOI: 10.1055/s-1979-28558

Upstream product

• 64-17-5 ethanol 
• 2274-73-9 1-(4-chlorophenyl)-2-(phenylthio)diazene 
• 139-65-1 4,4'-thiobisaniline 
• 139-66-2 diphenyl sulfide 
• 945-51-7 1,1'-sulfinylbisbenzene 
• 13343-26-5 phenyl p-chlorophenyl sulfide 
• 106-47-8 4-chloro-aniline 
• 108-90-7 chlorobenzene 
• 106-46-7 para-dichlorobenzene 
• 3085-42-5 bis(4-chlorophenyl)sulfoxide 
• 933-01-7 4-chloro-benzenesulfenyl chloride 
• 7446-70-0 aluminium trichloride 
• 7782-50-5 chlorine 
• 64-19-7 acetic acid 

Downstream Products

• 3085-42-5 bis(4-chlorophenyl)sulfoxide 
• 80-07-9 4,4'-dichlorodiphenyl sulphone 
• 24824-20-2 dichloro-bis-(4-chloro-phenyl)-λ⁴-sulfane 
• 132-65-0 dibenzothiophene 
• 106-46-7 para-dichlorobenzene 
• 127855-18-9 bis(4-chlorophenyl)phenylsulfonium hexafluoroantimonate 
• 1205-71-6 N-(4-chlorophenyl)aniline 
• 106-54-7 p-Chlorothiophenol 

Relevant articles and documents

Palladium Complex Immobilized on Magnetic Nanoparticles Modified with 2-Aminopyridine Ligand: A Novel and Efficient Recoverable Nanocatalyst for C–S and C–Se Coupling Reactions

A novel, versatile and efficient magnetically recoverable palladium nanocatalyst [Fe3O4@SiO2/2-aminopyridine-Pd(II)] was fabricated via the immobilization of palladium(II) complex on the surface of magnetic nanoparticles modified with 2-aminopyridine ligand. The structure of the as-fabricated Fe3O4@SiO2/2-aminopyridine-Pd(II) nanocomposite was characterized by a series of spectroscopic techniques including FT-IR, SEM, TEM, EDX, TGA, XRD, VSM and ICP-OES techniques. The Fe3O4@SiO2/2-aminopyridine-Pd(II) nanocomposite was utilized under mild and eco-friendly conditions in C–S and C–Se coupling reactions to afford a vast variety of diaryl sulfides and diaryl selenides with good to excellent yields. This heterogeneous palladium catalyst can be magnetically separated and reused for at least 7 consecutive trials without any reduction in activity. Graphical Abstract: [Figure not available: see fulltext.]

Scalable electrochemical reduction of sulfoxides to sulfides

A scalable reduction of sulfoxides to sulfides in a sustainable way remains an unmet challenge. This report discloses an electrochemical reduction of sulfoxides on a large scale (>10 g) under mild reaction conditions. Sulfoxides are activated using a substoichiometric amount of the Lewis acid AlCl3, which could be regeneratedviaa combination of inexpensive aluminum anode with chloride anion. This deoxygenation process features a broad substrate scope, including acid-labile substrates and drug molecules.

Selective synthesis of sulfoxides and sulfonesviacontrollable oxidation of sulfides withN-fluorobenzenesulfonimide

A practical and mild method for the switchable synthesis of sulfoxides or sulfonesviaselective oxidation of sulfides using cheapN-fluorobenzenesulfonimide (NFSI) as the oxidant has been developed. These highly chemoselective transformations were simply achieved by varying the NFSI loading with H2O as the green solvent and oxygen source without any additives. The good functional group tolerance makes the strategy valuable.