51849-53-7Relevant articles and documents
Rhodium-catalyzed direct C - H addition of 4,4-dimethyl-2-oxazoline to alkenes
Wiedemann, Sean H.,Bergman, Robert G.,Ellman, Jonathan A.
, p. 1685 - 1687 (2007/10/03)
A new method for the preparation of 2-substituted oxazolines by rhodium-catalyzed coupling of alkenes with 4,4-dimethyl-2-oxazoline is reported. The oxazoline products are obtained in good yield with excellent selectivity for the linear product. A variety of alkene substitution patterns and functional groups are tolerated. This procedure represents an attractive alternative to hydroesterification because it does not involve the manipulation of CO gas.