4-[N,N-Bis(2-chloroethyl)amino]phenylarsonic acid, also known as phenylarsine oxide or PAO, is a chemical compound with the molecular formula C8H12AsCl2NO2. It is an organoarsenic compound that has been used as a chemotherapeutic agent, particularly in the treatment of certain types of cancer. PAO works by inhibiting the enzyme dihydrofolate reductase, which is essential for DNA synthesis and cell division. This action leads to the disruption of DNA replication and ultimately cell death. The compound is characterized by its potential toxicity and has been largely replaced by less toxic alternatives in modern cancer treatment. It is important to note that due to its hazardous nature, handling and use of PAO are subject to strict safety protocols and regulations.
5185-71-7
Post Buying Request-
-
Basic information
- Product Name: 4-[N,N-Bis(2-chloroethyl)amino]phenylarsonic acid
- Synonyms: 4-[N,N-Bis(2-chloroethyl)amino]phenylarsonic acid
- CAS NO:5185-71-7
- Molecular Formula: C10H14AsCl2NO3
- Molecular Weight: 342.07
- EINECS: N/A
- Product Categories: N/A
- Mol File: 5185-71-7.mol
-
Chemical Properties
- Melting Point: N/A
- Boiling Point: 111°C
- Flash Point: 290.6°C
- Appearance: /
- Density: g/cm3
- Vapor Pressure: 3.09E-13mmHg at 25°C
- Refractive Index: N/A
- Storage Temp.: N/A
- Solubility: N/A
- CAS DataBase Reference: 4-[N,N-Bis(2-chloroethyl)amino]phenylarsonic acid(CAS DataBase Reference)
- NIST Chemistry Reference: 4-[N,N-Bis(2-chloroethyl)amino]phenylarsonic acid(5185-71-7)
- EPA Substance Registry System: 4-[N,N-Bis(2-chloroethyl)amino]phenylarsonic acid(5185-71-7)
-
Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- WGK Germany:
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 5185-71-7(Hazardous Substances Data)
5185-71-7 Suppliers
Recommended suppliers
5185-71-7 Usage
Check Digit Verification of cas no
The CAS Registry Mumber 5185-71-7 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,1,8 and 5 respectively; the second part has 2 digits, 7 and 1 respectively.Calculate Digit Verification of CAS Registry Number 5185-71:
(6*5)+(5*1)+(4*8)+(3*5)+(2*7)+(1*1)=97
97 % 10 = 7
So 5185-71-7 is a valid CAS Registry Number.
InChI:InChI=1/C10H14AsCl2NO3/c12-5-7-14(8-6-13)10-3-1-9(2-4-10)11(15,16)17/h1-4H,5-8H2,(H2,15,16,17)
5185-71-7Upstream product
5185-71-7Downstream Products
Post a RFQ
1
What can I do for you?
Get Best Price
Get Best Price for 5185-71-7
4-[N,N-Bis(2-chloroethyl)amino]phenylarsonic acid
