51952-34-2

Basic information

• Product Name: (S)-2-(2-(((benzyloxy)carbonyl)amino)-3-(4-(benzyloxy)phenyl)propanamido)acetic acid
• Synonyms: (S)-2-(2-(((benzyloxy)carbonyl)amino)-3-(4-(benzyloxy)phenyl)propanamido)acetic acid
• CAS NO: 51952-34-2
• Molecular Weight: 462.502
• Mol File: 51952-34-2.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: (S)-2-(2-(((benzyloxy)carbonyl)amino)-3-(4-(benzyloxy)phenyl)propanamido)acetic acid(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-2-(2-(((benzyloxy)carbonyl)amino)-3-(4-(benzyloxy)phenyl)propanamido)acetic acid(51952-34-2)
• EPA Substance Registry System: (S)-2-(2-(((benzyloxy)carbonyl)amino)-3-(4-(benzyloxy)phenyl)propanamido)acetic acid(51952-34-2)

Safety Data

• Hazardous Substances Data: 51952-34-2(Hazardous Substances Data)

Upstream product

• 1429433-81-7 Cbz-Tyr-(OBn)-Bt 
• 56-40-6 glycine 
• 86827-18-1 N-benzyloxycarbonyl-O-benzyl-L-tyrosine 
• 16677-35-3 N-benzyloxycarbonyl-O-benzyl-(S)tyrosyl-glycine methyl ester 
• 21869-36-3 N-(O-benzyl-N-benzyloxycarbonyl-L-tyrosyl)-glycine ethyl ester 

Downstream Products

• 51952-35-3 Z-Tyr(CH₂Ph)-Gly-NH-NH-Boc 
• 96914-85-1 C₅₆H₆₂N₅O₁₀P 
• 145763-38-8 N-benzyloxycarbonyl-O-benzyl-(S)tyrosyl-glycyl-glycyl-(Z)dehydrophenylalanyl(S)leucine methyl ester 
• 145763-53-7 C₄₄H₄₉⁽²⁾H₂N₅O₉ 
• 85541-25-9 N-benzyloxycarbonyl-O-benzyl-L-tyrosylglycylglycyl-L-phenylalanyl-L-leucine methyl ester 
• 1429433-65-7 C₄₃H₅₀N₆O₉ 
• 1429433-64-6 Cbz-Tyr(OBn)-Gly-Bt 
• 96914-93-1 N-<<<(tyrosylglycyl)amino>methyl>hydroxyphosphinyl>phenylalanylleucine disodium salt 
• 673-08-5 YG 

Relevant articles and documents

Benzotriazole-mediated synthesis of aza-peptides: En route to an aza-leuenkephalin analogue

Novel N-(N-Pg-azadipeptidoyl)benzotriazoles 20a-e couple efficiently with α-amino acids 21a-e, dipeptides 22a-c, aminoxyacetic acid 23a, depsidipeptide 23b, and α-hydroxy-β-phenylpropionic acid 27 yielding, respectively, azatripeptides 24a-g, azatetrapeptides 25a,b, a hybrid azatripeptide with an oxyamide bond 26a, a hybrid azatetrapeptide with an ester bond 26b, and a hybrid azatripeptide with an ester bond 28. A new protocol for the synthesis of N-Pg-azatripeptides 33a,b and 35a,b, each containing a natural amino acid at the N-terminus, avoids the low coupling rates of the aza-amino acid residue and enables the solution-phase synthesis of an azaphenylalanine analogue of Leu-enkephalin 40.

Synthesis and biological evaluation of phosphonamidate peptide inhibitors of enkephalinase and angiotensin-converting enzyme

The effectiveness of phosphonamidate peptide analogues as inhibitors of rat kidney or human brain metallo-endopeptidase (enkephalinase, E.C. 3.4.24.11) and angiotensin-converting enzyme (ACE, 3.4.15.1) has been explored with a series of enkephalin analogu

Luteinizing hormone releasing hormone and analogs. Synthesis and biological activity

A fragment synthesis of LH RH is described which lends itself to large scale preparation. Fragment 1-3 is coupled with fragment 4-6 followed by reaction with the tetrapeptide 7-10 to yield the unprotected decapeptide. The preparation of analogs follows the same synthetic pattern. The biological activity of the analogs is compared with that of synthetic LH RH.