51964-16-0

Basic information

• Product Name: 3-(4-bromophenyl)-2-(4-bromophenylimino)thiazolidin-4-one
• Synonyms: 3-(4-bromophenyl)-2-(4-bromophenylimino)thiazolidin-4-one
• CAS NO: 51964-16-0
• Molecular Weight: 426.131
• Mol File: 51964-16-0.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 3-(4-bromophenyl)-2-(4-bromophenylimino)thiazolidin-4-one(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(4-bromophenyl)-2-(4-bromophenylimino)thiazolidin-4-one(51964-16-0)
• EPA Substance Registry System: 3-(4-bromophenyl)-2-(4-bromophenylimino)thiazolidin-4-one(51964-16-0)

Safety Data

• Hazardous Substances Data: 51964-16-0(Hazardous Substances Data)

Upstream product

• 2059-75-8 N,N'-bis(p-bromophenyl)thiourea 
• 105-39-5 chloroacetic acid ethyl ester 
• 79-08-3 bromoacetic acid 
• 105-36-2 ethyl bromoacetate 
• 106-40-1 4-bromo-aniline 
• 79-11-8 chloroacetic acid 

Downstream Products

• 51963-97-4 3-[3-(4-bromo-phenyl)-2-(4-bromo-phenylimino)-4-oxo-thiazolidin-5-ylidene]-1,3-dihydro-indol-2-one 
• 1352834-11-7 4-[3-(4-bromophenyl)-2-(4-bromophenylimino)-4-oxothiazolidin-5-ylidenemethyl]benzoic acid 
• 1352834-17-3 {4-[3-(4-bromophenyl)-2-(4-bromophenylimino)-4-oxothiazolidin-5-ylidenemethyl]phenoxy}acetic acid 

Relevant articles and documents

Novel non-peptidic small molecule inhibitors of secreted aspartic protease 2 (SAP2) for the treatment of resistant fungal infections

Targeting secreted aspartic protease 2 (SAP2), a kind of virulence factor, represents a new strategy for antifungal drug discovery. In this report, the first-generation of small molecule SAP2 inhibitors was rationally designed and optimized using a structure-based approach. In particular, inhibitor 23h was highly potent and selective and showed good antifungal potency for the treatment of resistant Candida albicans infections.

Synthesis and biological evaluation of halogenated 2-arylimino-3- arythiazolidine-4-ones containing benzoic acid fragments as antibacterial agents

A series of halogenated 2-arylimino-3-ary-thiazolidine-4-ones containing (5-furan-2-yl)-benzoic acid or (5-thiophene-2-yl)-benzoic acid fragments was synthesized, and evaluated in vitro for their antibacterial activity, antibiofilm activity, erythrocyte h