5198-67-4Relevant academic research and scientific papers
Silver-free activation of ligated gold(I) chlorides: The use of [Me3NB12Cl11]- as a weakly coordinating anion in homogeneous gold catalysis
Wegener, Michael,Huber, Florian,Bolli, Christoph,Jenne, Carsten,Kirsch, Stefan F.
supporting information, p. 1328 - 1336 (2015/02/05)
Phosphane and N-heterocyclic carbene ligated gold(I) chlorides can be effectively activated by Na[Me3NB12Cl11] (1) under silver-free conditions. This activation method with a weakly coordinating closo-dodecaborate anion was shown to be suitable for a large variety of reactions known to be catalyzed by homogeneous gold species, ranging from carbocyclizations to heterocyclizations. Additionally, the capability of 1 in a previously unknown conversion of 5-silyloxy-1,6-allenynes was demonstrated.
Reactivity of 3-silyloxy-1,4-enynes: Gold(III)-catalyzed regioselective nucleophilic substitution
Haug, Timm T.,Harschneck, Tobias,Duschek, Alexander,Lee, Chang-Uk,Binder, J?rg T.,Menz, Helge,Kirsch, Stefan F.
scheme or table, p. 510 - 514 (2009/06/05)
Gold-catalyzed reactions of 3-silyloxy-1,4-enynes with alcohols afford primary, secondary, and tertiary pent-2-en-4-ynyl ethers in moderate to excellent yields. The substitution proceeds with high regioselectivity. An initial cyclization providing five-me
Pt-catalyzed cyclization/migration of propargylic alcohols for the synthesis of 3(2H)-furanones, pyrrolones, indolizines, and indolizinones
Bunnelle, Eric M.,Smith, Cameron R.,Lee, Sharon K.,Singaram, Surendra W.,Rhodes, Allison J.,Sarpong, Richmond
, p. 7008 - 7014 (2008/09/21)
Several heterocycles such as furanones, pyrrolones, and indolizines, which are of pharmacological importance, are easily accessed via the Pt(II)-catalyzed heterocyclization/1,2-migration of propargylic ketols or hydroxy imine derivatives. This method sidesteps the challenges of traditional heteroaromatic oxygenation strategies such as regioselectivity and functional group tolerance in the syntheses of these heterocycles.
Synthesis of heterocyclic systems by transition-metal-catalyzed cyclization-migration reactions - A diversity-oriented strategy for the construction of spirocyclic 3(2H)-furanones and 3-pyrrolones
Binder, Joerg T.,Crone, Benedikt,Kirsch, Stefan F.,Liebert, Clemence,Menz, Helge
, p. 1636 - 1647 (2008/02/06)
Two platinum(II)-catalyzed heterocyclization-migration reactions that provide five-membered heterocycle products are described. With 5 mol-% of PtCl2 as a catalyst, 2-alkynyl-2-hydroxy carbonyl compounds 1 are converted into 3(2H)-furanones 2 a
Gold(III)- and platinum(II)-catalyzed domino reaction consisting of heterocyclization and 1,2-migration: Efficient synthesis of highly substituted 3(2H)-furanones
Kirsch, Stefan F.,Binder, Joerg T.,Liebert, Clemence,Menz, Helge
, p. 5878 - 5880 (2007/10/03)
(Chemical Equation Presented) PtCl2-catalyzed alkyne activation initiates a domino reaction, in which a heterocyclization is followed by a 1,2-alkyl migration, for the construction of a variety of substituted 3(2H)-furanones. This stereospecifi
