51986-17-5

Basic information

• Product Name: Ethyl 5-hydroxy-1-methyl-1H-pyrazole-3-carboxylate
• Synonyms: Ethyl 5-hydroxy-1-methyl-1H-pyrazole-3-carboxylate;Ethyl,1-methylpyrazole-4-carboxylate;Ethyl 5-Hydroxy-1-Methylpyrazole-3-carboxylate;1H-Pyrazole-3-carboxylic acid, 5-hydroxy-1-Methyl-, ethyl ester;5-Hydroxy-1-methyl-1H-pyrazole-3-carboxylicacidethylester
• CAS NO: 51986-17-5
• Molecular Formula: C₇H₁₀N₂O₃
• Molecular Weight: 170.17
• Mol File: 51986-17-5.mol
• Article Data: 10

Chemical Properties

• Melting Point: 140-141 °C
• Boiling Point: 337.216 °C at 760 mmHg
• Flash Point: 157.743 °C
• Appearance: /
• Density: 1.29 g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.551
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 8.31±0.28(Predicted)
• CAS DataBase Reference: Ethyl 5-hydroxy-1-methyl-1H-pyrazole-3-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: Ethyl 5-hydroxy-1-methyl-1H-pyrazole-3-carboxylate(51986-17-5)
• EPA Substance Registry System: Ethyl 5-hydroxy-1-methyl-1H-pyrazole-3-carboxylate(51986-17-5)

Safety Data

• Hazardous Substances Data: 51986-17-5(Hazardous Substances Data)

Usage

General Description

Ethyl 5-hydroxy-1-methyl-1H-pyrazole-3-carboxylate is a chemical compound with the molecular formula C7H10N2O3. It is a derivative of pyrazole, a heterocyclic organic compound. This chemical is commonly used in the pharmaceutical industry as an intermediate for the synthesis of various drugs and medicines. It has potential medicinal properties due to its structural features, including the presence of a hydroxy group and a carboxylate moiety. Ethyl 5-hydroxy-1-methyl-1H-pyrazole-3-carboxylate may have applications in the treatment of various diseases and conditions due to its biological activity and potential pharmacological effects. Further research and studies are needed to fully understand the pharmacological properties and potential uses of this compound.

InChI:InChI=1/C7H10N2O3/c1-3-12-7(11)5-4-6(10)9(2)8-5/h4,10H,3H2,1-2H3

Upstream product

• 7339-53-9 methyl hydrazine hydrochloride 
• 40876-98-0 sodium 1,4-diethoxy-1,4-dioxobut-2-en-2-olate 
• 64-17-5 ethanol 
• 687-00-3 methyl 4,4,4-trichloroacetoacetate 
• 3702-98-5 ethyl 4,4,4-trichloroacetoacetate 
• 60-34-4 methylhydrazine 
• 762-21-0 acetylenedicarboxylic acid diethyl ester 
• 302-15-8 methylhydrazine sulfuric acid 
• 88330-76-1 diethyl oxalacetate sodium salt 

Downstream Products

• 85230-31-5 4-(4-Chloro-phenylcarbamoyl)-5-hydroxy-1-methyl-1H-pyrazole-3-carboxylic acid ethyl ester 
• 85230-34-8 5-Hydroxy-1-methyl-4-o-tolylcarbamoyl-1H-pyrazole-3-carboxylic acid ethyl ester 
• 85230-32-6 4-(2,5-Dichloro-phenylcarbamoyl)-5-hydroxy-1-methyl-1H-pyrazole-3-carboxylic acid ethyl ester 
• 81292-21-9 3-(3-ethoxycarbonyl-5-hydroxy-1-methylpyrazol-4-yl)-N-propylpropanamide 
• 58364-97-9 5-hydroxy-1-methyl-1h-pyrazole-3-carboxylic acid 
• 946061-21-8 5-chloro-4-formyl-1-methyl-1H-pyrazole-3-carboxylic acid ethyl ester 
• 1269293-48-2 ethyl 5-bromo-1-methyl-1H-pyrazole-3-carboxylate 
• 85230-35-9 5-Hydroxy-1-methyl-4-(3-trifluoromethyl-phenylcarbamoyl)-1H-pyrazole-3-carboxylic acid ethyl ester 
• 85230-30-4 4-(3-Chloro-phenylcarbamoyl)-5-hydroxy-1-methyl-1H-pyrazole-3-carboxylic acid ethyl ester 
• 81292-17-3 3-ethoxycarbonyl-1-methylpyrano<2,3-c>pyrazol-6(1H)-one 
• 85230-28-0 3-ethoxycarbonyl-1-methyl-4-(N-phenylcarbamoyl)pyrazolin-5-one 
• 85230-29-1 4-(2-Chloro-phenylcarbamoyl)-5-hydroxy-1-methyl-1H-pyrazole-3-carboxylic acid ethyl ester 

Relevant articles and documents

Synthesis method of 5-bromine-1-methyl-1H-pyrazole-3-amine

The invention discloses a synthesis method of 5-bromine-1-methyl-1H-pyrazole-3-amine. The method comprises the steps of condensing diethyl butynedioate serving as a raw material with methylhydrazine to obtain 5-hydroxyl-1-methyl-1H-pyrazole-3-carboxylic acid ethyl ester, and reacting the 5-hydroxyl-1-methyl-1H-pyrazole-3-carboxylic acid ethyl ester with phosphorus oxybromide to obtain 5-bromine-1-methyl-1H-pyrazole-3-carboxylic acid ethyl ester; hydrolyzing in a sodium hydroxide alcohol solution to obtain 5-bromine-1-methyl-1H-pyrazole-3-carboxylic acid, reacting the 5-bromine-1-methyl-1H-pyrazole-3-carboxylic acid with dimethyl azide phosphate and tert-butyl alcohol to obtain tert-butyl (5-bromine-1-methyl-1H-pyrazole-3-yl) carbamate, and hydrolyzing in trifluoroacetic acid to obtain the5-bromine-1-methyl-1H-pyrazole-3-amine. The method has the advantages of simple synthesis route, reasonable process selection, low raw material cost, simple and easily available raw materials, convenient operation and post-treatment, and no use of highly toxic reagents, and overcomes the defects of expensive and unavailable raw materials, unsafe operation, difficult amplification and the like in the existing synthesis process.

COMPOUNDS AND USES THEREOF

The present invention features compounds useful in the treatment of neurological disorders. The compounds of the invention, alone or in combination with other pharmaceutically active agents, can be used for treating or preventing neurological disorders.

TRISAZO-DYES WITH A PYRAZOLYL END GROUP AND THEIR USE IN INK-JET PRINTING

A compound of Formula (1) or a salt thereof: A-N=N-D-N=N-B-N=N-A' wherein A is an optionally substituted aryl, heteroaryl, non-aromatic heterocyclic or alkenyl group; D is an optionally substituted, optionally metallised 1,8-dihydroxynaphthalene group; B is an optionally substituted organic linking group; and A' is an optionally substituted pyrazolyl group which does not have an aromatic group as a substituent directly attached to either of the nitrogen atoms of the pyrazolyl ring. Also provided are compositions, inks, ink sets, substrates and cartridges all containing the compound or salt and printing processes using the compound or salt. The compounds and salts are especially useful for ink-jet printing.